B. Nyamambi, L.R. Ndlovu, Y.S. Naik and N.D. Kock 1 Departments of Animal Science, Biochemistry and Veterinary Paraclinical Studies, University of Zimbabwe, Box MP 167, Mount Pleasant, Harare, Zimbabwe 2 Department of Environmental Science and Health, National University of Science and Technology, Bulawayo, Zimbabwe 3 Department of Pathology-Comparative Medicine, Medical Centre Boulevard, Schoo...

A micellar electrokinetic chromatographic (MEKC) method has been established for the identification and determination of acid-catalyzed proanthocyanidin cleavage products in the presence of phloroglucinol. Using fused-silica capillaries (50=57 cm, 22 kV) with phosphate buffer containing sodium dodecyl sulfate as the surfactant and b-cyclodextrin as modifier, structurally similar phloroglucinol ...

A prune extract was separated by an antioxidant-guided assay to obtain an oligomeric proanthocyanidin fraction. The antioxidative oligomer was characterized as a procyanidin oligomer with an average polymerization degree of five and composed of epicatechin and catechin units. The antioxidative activity of the oligomer showed greater potency than chlorogenic acid which is known as an antioxidati...

The pathogenesis of periodontitis involves anaerobic oral bacteria as well as the host response to infection and several drugs have been developed which can curtail these deleterious effects. Proanthocyanidin, a novel flavanoid extracted from grape seeds, has been shown to provide a significant therapeutic effect on endotoxin (Escherichia coli) induced experimental periodontitis in rats. In thi...