objectives : platelet preparations are commonly used to enhance bone and soft tissue regeneration. considering the existing controversies on the efficacy of platelet products for tissue regeneration, more in vitro studies are required. the aim of the present study was to compare the in vitro effects of plasma rich in growth factors (prgf) and platelet-rich fibrin (prf) on proliferation and viab...

Plant-derived compounds are a reservoir of natural chemicals and can act as drug precursors or prototypes pharmacological probes. Methoxyeugenol is compound found in plant extracts, such nutmeg ( Myristica fragrans ), it presents anthelmintic, antimicrobial, anti-inflammatory activities. Recently, interest the anticancer activity extracts increasing therapeutic methoxyeugenol against cancer has...

Short title: Cytotoxic vs. Proliferation Capacity of Memory CD8 T-Cells

OBJECTIVES To compare the proliferative and chondrogenic potential of fresh and frozen chondrocytes isolated from superficial and deep articular cartilage biopsies. MATERIALS AND METHODOLOGY The study included 12 samples of fresh and frozen healthy human knee articular cartilage. Cell proliferation was tested at 3, 6 and 9 days. Studies of mRNA quantification, protein expression and immunoflu...

objective: by date investigations have indicated the presence of stem cells within the pulp tissue of both temporary and permanent human teeth. in the present study, these stem cells were compared in terms of their growth kinetics and culture requirements. materials and methods: stem cells within the pulp of the human third molar (permanent tooth) and the deciduous incisor (temporary tooth) wer...

RATIONALE Cardiomyocytes in adult mammalian hearts are terminally differentiated cells that have exited from the cell cycle and lost most of their proliferative capacity. Death of mature cardiomyocytes in pathological cardiac conditions and the lack of regeneration capacity of adult hearts are primary causes of heart failure and mortality. However, how cardiomyocyte proliferation in postnatal a...

Severe fetal growth restriction (FGR) is characterized by increased placental vascular resistance resulting from aberrant angiogenesis. Interactions between endothelial cells (ECs) and the extracellular matrix (ECM) are critical to complex process of We have previously found that stromal abnormalities contribute impaired angiogenesis in severe FGR. The objective this research better characteriz...

Mesenchymal stem cells (MSCs) showed in vitro mesoderm-lineage differentiation and self-renewal capacity. However, no comparative study was reported on the biological characteristics of derived from skeletal muscle (SM-MSCs), dermal skin (DS-MSCs), adipose tissues (A-MSCs) a single donor camels. The present aimed to evaluate influence MSCs source cell characteristics. We evaluated proliferation...