Immunization is one of the most effective and cost-effective prevention measures available. As a result of universal vaccination of children, polio has been eliminated in the United States and much of the world, measles and rubella are no longer endemic diseases in the United States, and most of the other vaccine-preventable diseases of childhood are at or near record lows. A recent review of c...

for teenagers in Japan The editorial by Butler & Malone focused on non-suicidal selfinjury (NSSI), proposed as a new category in DSM-5, and described the criteria of this item. The authors also provided information about NSSI among young people. In Japan in August 2012, the Japanese Cabinet decided to enhance suicide prevention measures for younger people, given the increasing suicide rate amon...

background: microorganisms that cause early neonatal sepsis are usually already colonized rectovaginal area in mothers. the most common of these organisms is group b streptococci (gbs) and intestinal gram-negative bacteria mostly escherichia coli (e.coli). the use of prophylactic antibiotics against gbs has increased in recent years. this study aimed to determine the current situation and frequ...

BACKGROUND Findings from several studies suggest that bilateral prophylactic mastectomy reduces breast cancer incidence by 90% or more, but the studies used highly selected patients from referral centers, and the comparison groups were not population based. We studied the efficacy of bilateral prophylactic mastectomy in women with elevated breast cancer risk cared for in community practices. ...

PURPOSE Prophylactic antibiotics have been used in acute necrotizing pancreatitis with mixed results. This meta-analysis analyzes the effects of prophylactic antibiotics in necrotizing pancreatitis. METHODS Multiple databases and abstracts were searched for randomized trials comparing treatment with prophylactic antibiotics to treatment without prophylactic antibiotics in necrotizing pancreat...

BACKGROUND Increasingly, prophylactic mastectomy has been evaluated as a treatment of breast cancer. Hereditary breast cancer now accounts for approximately 5%-10% of all cases of breast cancer, meaning that the widespread implementation of prophylactic mastectomy may significantly reduce the occurrence of breast cancer. However, prophylactic mastectomy is rarely performed in Korea. Therefore, ...

  Absract   Gastric cancer is the fourth most common cancer and the second leading cause of   cancer death. Most cases are sporadic and only 10% of patients, show familial clustering. Among these patients, 1 to 3 % have hereditary diffuse gastric cancer   (HDGC), which is autosomal-dominant and present in younger ages. Mutations in Ecadherin gene CDH1 has been identified in 30 to 50% of patient...