Prostate cancer is the most common nonskin malignant neoplasm in men worldwide. In the United States, 241,740 new diagnoses of prostate cancer and 28,170 prostate cancer deaths have been estimated for 2012, representing 28% of new cancer cases and 10% of male cancer deaths.(1) Although metastatic prostate cancer remains an incurable disease, substantial advances have been made in therapeutic op...

Sarcomatoid carcinoma of prostate is an extremely rare but aggressive neoplasm. It is generally associated with a poor prognosis. About 100 cases have so far been reported in the English literature. We report the case of a 64-year-old male with a very rapidly progressive disease that ultimately involved the whole lower urinary tract and rectum. The management of this case along with etio-pathog...

Prostate cancer is the most common non-cutaneous neoplasm in the male population worldwide. It is typically diagnosed in its early stages, and the disease exhibits a relatively indolent course in most patients. Despite the curability of localized disease with prostatectomy and radiation therapy, some patients develop metastatic disease and die. Although androgen deprivation is present in the ma...

A 51-year-old male smoker presented with gross hematuria and obstructive voiding symptoms. Digital rectal examination was notable for a palpable abnormality of the prostate. Prostate specific antigen (PSA) level was 0.4 g/ml. Basic laboratory values, urinalysis, cytology and cystoscopic examination were within normal limits. Ultrasound guided prostate needle biopsy demonstrated sarcomatoid carc...

BACKGROUND Prostate cancer is the most common neoplasm of American men and the second most common cause of cancer-related deaths. Research suggests that infection and subsequent inflammation may be an important risk factor in the pathogenesis of prostate cancer. In this meta-analysis, we examine the current epidemiological evidence for the association between specific sexually transmitted disea...

BACKGROUND Atherosclerotic disease is the most common cause of death in the United States and prostate cancer has the highest incidence among males in the United States. Reports have indicated that atherosclerosis and cancers my share common pathoetiologic and pathogenetic cascades. If atherosclerosis and cancers have common pathoetiologic and pathogenetic cascades, both diseases will co-occur ...

Prostate cancer is the most common nonskin malignant neoplasm in men worldwide. In the United States, 241,740 new diagnoses of prostate cancer and 28,170 prostate cancer deaths have been estimated for 2012, representing 28% of new cancer cases and 10% of male cancer deaths.(1) Although metastatic prostate cancer remains an incurable disease, substantial advances have been made in therapeutic op...

INTRODUCTION Prostate cancer (PC) treatment in early stages is radical prostatectomy (RP) or external radiotherapy (ER). There is some uncertainty regarding the development of new ER induced malignant tumors or second primary tumor (SPT), a fact influencing the choice of therapy. The purpose of this study is to determine the best therapeutic alternative for localized PC, in regards to incidence...

PURPOSE Mitochondrial DNA (mtDNA) gene mutations have been described in nearly every adult solid neoplasm including prostate cancer. There are marked racial differences in specific inherited mutations within the cytochrome c oxidase subunit 1 (COI) gene in individuals with prostate cancer (PCa). The purpose of this study was to identify the variation in COI gene sequence in prostate cancer pati...

Han Jung, Han Sae Lee, Sang Jin Yoon, Khae Hawn Kim From the Department of Urology, Gachon University Gil Hospital, Incheon, Korea Prostatic ductal adenocarcinoma is a rare neoplasm that develops from the prostatic urethra. We present an 85-year-old man with an exophytic lesion in the prostatic cavity, which was diagnosed after transurethral resection of the prostate. Histopathologically, the t...