نتایج جستجو برای: prostate specific membrane antigen
تعداد نتایج: 1576824 فیلتر نتایج به سال:
Recently, a novel M(r) 100,000 prostate-specific membrane glycoprotein (PSM) has been detected by the prostate-specific monoclonal antibody 7E11-C5, raised against the human prostatic carcinoma cell line LNCaP. The PSM antigen is expressed exclusively by normal and neoplastic prostate cells and metastases. We now report the molecular cloning of a full-length 2.65-kilobase complementary DNA enco...
Recently, a novel Mr 100,000 prostate-specific membrane glycoprotein (PSM) has been detected by the prostate-specific monoclonal antibody 7Ell-C5, raised against the human prostatic carcinoma cell line LNCaP. The PSM antigen is expressed exclusively by normal and neoplastic prostate cells and metastases. We now report the molecular cloning of a full-length 2.65-kilobase complementary DNA encodi...
Background and Objective: Non-specific granulomatous prostatitis is an uncommon diffuse inflammatory condition of the prostate. It is important because it may be mistaken for prostatic carcinoma. The aim of the study was to determine the prevalence of non-specific granulomatous prostatitis (NSGP) and comparing the results of transrectal ultrasonography, serum prostate specific antigen (PSA) ...
Recently, a novel Mr 100,000 prostate-specific membrane glycoprotein (PSM) has been detected by the prostate-specific monoclonal antibody 7Ell-C5, raised against the human prostatic carcinoma cell line LNCaP. The PSM antigen is expressed exclusively by normal and neoplastic prostate cells and metastases. We now report the molecular cloning of a full-length 2.65-kilobase complementary DNA encodi...
Background: Due to its biological properties, Prostate-specific membrane antigen (PSMA) is a good target for prostate cancer molecular imaging. The aim of this work was evaluate the role 18F PSMA Tomography–Computed Tomography (PET CT) in diagnosis and staging association with specific serum level. Methods: This prospective cohort performed on 30 individuals pathologically proven patients, seve...
Abstract Background: Removal of prostate and radiotherapy are used routinely for treatment of prostate cancer however in advanced stages of the disease these treatments are ineffective. Researchers are exploring strategies for preventing this malignancy. This study aims to design and develop a phage based vaccine for preventing prostate cancer. Materials and methods: After conducting bioinforma...
Background: Prostate-Specific Antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is the best marker for early diagnosis of prostate cancer. Since age and race are affecting PSA levels, determining age-specific reference ranges of PSA in every community is necessary for increasing the efficiency rate of PSA. The aim of the present study was to evaluate the normal distributi...
BACKGROUND The present study was undertaken to relate the co-expression of prostate-associated antigens, PSMA and PSA, with the degree of vascularization in normal and pathologic (hyperplasia and cancer) prostate tissues to elucidate their possible role in tumor progression. METHODS The study was carried out in 6 normal, 44 benign prostatic hyperplastic and 39 cancerous human prostates. Immun...
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