Colon cancer constitutes a major challenge all over the world, which has fourth highest incidence and third mortality rate of cancers. Although therapeutic modalities have been improved in recent years, 5 y survival remains low. Oxymatrine is one main active compounds extracted from roots Sophora flavescens was found with effect for colon Recently, microRNAs recognized as type diagnostic progno...

during past few years, the cupressus arizonica has been abundantly planted in tehran, causing a significant increase of allergic diseases from the middle of winter to the beginning of spring. the aim of this study was the comparison of pollen protein content in two major varieties of c. arizonica planted in tehran, including c. arizonica var. arizonica and c. arizonica var. glabra , in order to...

soybean isoflavone genistein has multiple anticancer properties and its pro-apoptotic and anti-proliferative effects have been studied in different cancer cells. however, the mechanisms of action of genistein and its molecular targets on human colon cells have not been fully elucidated. therefore, caspase-3 and p38 mitogen-activated protein kinase (p38 mapk) as the main therapeutic targets were...

This study was conducted to determine the electrophoretic pattern of serum protein in goats infected withBabesia ovis. Serum total protein was calculated and serum electrophoresis from 15 goats naturally infectedwith B. ovis as well as same number of healthy goats was performed. Microscopic examination of Giemsastained peripheral blood smears revealed B. ovis infection. The parasitological diag...

Calprotectin, a calcium-bound protein complex, is abundant in the cytosol of neutrophils. It has been reported that this protein has an apoptotic activity in tumor cells. Since calprotectin increases in colorectal cancer, this study was conducted to investigate, for the first time, the cytotoxicity/apoptotic effect of calprotectin on HT29/219 and SW742 colon carcinoma and adenocarcinoma cell li...

Protein hydrolysates and peptides can show biological activities, pulsed ultrasound improves bioactivities. Among matrices from which protein be obtain, chickpea is an excellent source. The objective of this research was to evaluate the effect on globulin concentrate obtain hydrolysate (HGb) peptide fractions their bioactivity. Antioxidant activity by ABTS (2,2′-Azino-bis(3-ethylbenzothiazoline...