The review presents the results of clinical studies efficacy and safety Tenoten children’s in treatment anxiety, neurotic, stress-related somatoform disorders adjustment disorders. Technologically processed antibodies to S100 protein drugs change conformation protein, which is considered as a pathological link development anxiety states, well neurodegenerative diseases. well-studied daytime anx...

Abstract We consider the problem of recovering three-dimensional atomic structure a flexible macromolecule from heterogeneous cryogenic electron microscopy (cryo-EM) dataset. The dataset contains noisy tomographic projections electrostatic potential macromolecule, taken different viewing directions, and in case, each cryo-EM image corresponds to conformation macromolecule. Under assumption that...

Pre-miR-675 is a microRNA expressed from the exon 1 of H19 long noncoding RNA, and atypical expression pre-miR-675 has been linked with several diseases disorders including cancer. To execute its function inside cell, folded into particular conformation, which aids in interaction other biological molecules. However, exact folding dynamics protein-binding motifs are currently unknown. Moreover, ...