Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

It is well-known that the typical protein’s three-dimensional structure is relatively unstable in harsh conditions. A practical approach to maintain the folded state and thus improve the stability and activity of proteins in unusual circumstances is to directly apply stabilizing substances such as osmolytes to the protein-containing solutions. Osmolytes as natural occurring organic molecules ty...

Proteomics enables understanding the composition, structure, function and interactions of the entire protein complement of a cell, a tissue, or an organism under exactly defined conditions. Some factors such as stress or drug effects will change the protein pattern and cause the present or absence of a protein or gradual variation in abundances. Changes in the proteome provide a snapshot of the...

A method for optimizing MR imaging pulse sequence parameters in a statistical framework is presented. Parameters are defined to be optimal when the resulting scalar images yield optimal image segmentations using Bayesian pixel classification. Thus, Bayes risk is used as the objective function to minimize. Approximations are made to give a tractable solution in a four-step procedure. A sample ca...

We propose differential holography as a method to overcome the long-standing forward-scattering problem in photoelectron holography and related techniques for the three-dimensional imaging of atoms. Atomic images reconstructed from experimental and theoretical Cu 3p holograms from Cu(001) demonstrate that this method suppresses strong forward-scattering effects so as to yield more accurate thre...

Mailing address: Marcelo Luiz Campos Vieira • Rua Cardoso de Melo, 463/21 04548-002 São Paulo, SP Brazil E-mail: [email protected] Manuscript received January 09, 2007; revised manuscript received January 01, 2007; accepted March 13, 2007. The use of three-dimensional echocardiography for the analysis of cardiac structures allows the viewing of planes that make the anatomic identification m...

The results of experiments in developing a method for extracting three-dimensional information from a scene by means of a polarimetric passive imaging sensor are summarized. This sensor provides a full Stokes vector at each sensor pixel location from which degree and angle of linear polarization are computed. The angle of linear polarization provides the azimuth angle of the surface normal vect...

This article addresses the current state of the art of technology in three-dimensional echocardiography as it applies to transducer design, beam forming, display, and quantification. Because three-dimensional echocardiography encompasses many technical and clinical areas, this article reviews its strengths and limitations and concludes with an analysis of what to use when.