C AFFEINISM, a diagnosis recently included in the third edition of the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders (DSM-III),’ is characterized by a constellation of affective, sleep, and psychophysiological manifestations.2 Because symptoms of caffeinism might be confounded or masked by simultaneous ingestion of other drugs, it is pertinent to ask w...

OBJECTIVE The relative risk of psychotropic medication use in women with puerperal psychiatric illness who are breastfeeding has yet to be quantified adequately. Although the emotional and medical benefits of breastfeeding and adverse effects of maternal depression on infant development are well described, how these absolute benefits weigh against the potential effects of psychotropic drug use ...

The interaction between the cognitive component (the perception of nociceptive, or painful stimuli) and the affective component of pain is reflected in the overlap between the actions of anti-nociceptive agents (analgesics) and mood-altering drugs (psychotropics) when treating pain patients. Anxiety, depression, fear and sleeplessness may all respond to psychotropic drugs, and this may result i...

105 Abstract: Psychiatric patients are at greater risk of sudden death, with a 3–5 fold increase compared with the nonpsychiatric population. Sudden death may arise from complications of the mental illnesses or as a result of psychotropic medication. Anorexia nervosa, drug use, alcohol misuse are the mental disorders most likely associated with sudden death. A variety of psychotropic drugs, par...

OBJECTIVE To explore the healthcare resource utilization, psychotropic drug use and mortality of older people with dementia. DESIGN A nationwide propensity score-matched cohort study. SETTING National Health Insurance Research database. PARTICIPANTS A total of 32,649 elderly people with dementia and their propensity-score matched controls (n=32,649). MEASUREMENTS Outpatient visits, inpa...

BACKGROUND AND OBJECTIVES Polyuria, polydipsia, and nephrogenic diabetes insipidus have been associated with use of psychotropic medications, especially lithium. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The impact of psychotropic medications on urinary concentrating ability and urinary aquaporin 2 (AQP2) excretion was investigated after overnight fluid deprivation, and over 6 h after 40 ...

INTRODUCTION The treatment of pediatric aggression often involves psychotropic agents. Despite growing research on pediatric psychopharmacology, however, clinical issues regarding medication management of persistent behavioral problems remain poorly addressed. METHOD A review of the literature from 1980 to November, 2005 yielded 45 randomized, placebo-controlled trials that addressed the trea...

OBJECTIVE Despite increasing use of psychotropic medications in children and adolescents, data regarding their efficacy and safety are limited. Endocrine and metabolic adverse effects are among the most concerning adverse effects of commonly used psychotropic medications. METHOD Selective review of endocrine and metabolic effects of psychotropic medications in pediatric populations, with a fo...