Electroporation can be used as an active enhancement method for intra- and transdermal drug delivery. Differences in response of skin to electric pulses depend on their amplitude, duration and number and have been a point of interest in the past. While protocols consisting of the same repetitive, mostly exponentially decaying pulses have been used before, this study is focused on comparing diff...

The tumor suppressor p53 protein shows various dynamic responses depending on the types and extent of cellular stresses. In particular, in response to DNA damage induced by γ-irradiation, cells generate a series of p53 pulses. Recent research has shown the importance of sustaining repeated p53 pulses for recovery from DNA damage. However, far too little attention has been paid to understanding ...

OBJECTIVE To evaluate the quantitative advantage of double pulses vs. single pulses in TMS phosphenes evoked from the occipital cortex. METHODS In 10 healthy subjects single pulse thresholds were compared with thresholds from double pulses of equal strength at a stimulus onset asynchrony (SOA) of 2, 5, 10, and 20ms, both with biphasic and monophasic pulse forms. In a second experiment fusion ...

A time-domain technique is proposed for ultra-wideband (UWB) microstrip-filter design. The design technique uses the reflection coefficient (S11) specified in the frequency domain. When the frequency response of the UWB filter is given, the response will be approximated by a series of UWB pulses in the time domain. The UWB pulses are Gaussian pulses of the same bandwidth with different time del...

We have conducted a search for giant pulses from four millisecond pulsars using the 100m Green Bank Telescope. Coherently dedispersed time-series from PSR J0218+4232 were found to contain giant pulses of very short intrinsic duration whose energies follow power-law statistics. The giant pulses are in phase with the two minima of the radio integrated pulse profile but are phase aligned with the ...

The pulses are belongs to the family Fabaceae which is also known as food legumes. Pulses are second important group of the crops after cereals. Pulses are the most important crops of Indian Agriculture. The member of Fabaceae family includes the economically important legume like pulses, oil seed, forage and fodder crops and also shrubs and tropical or subtropical trees. These pulses are chick...

Introduction Imaging sequences reliant upon non-selective refocusing (e.g., 3D TSE, 3D GraSE, and 3D SE-EPI) widely employ either block/sinc refocusing pulses susceptible to field inhomogeneities or adiabatic pulses that demand high SAR. The aim of this work was to evaluate a sample of short, low-SAR, non-selective refocusing pulses by comparing signals acquired with a 3D SE-EPI sequence at 7 T...

Existence and dynamics of chaotic pulses on 1D lattice are discussed. Traveling pulses arise typically in reaction diffusion systems like the FitzHugh-Nagumo equations. Such pulses annihilate when they collide each other. A new type of traveling pulse has been found recently in many systems where pulses bounce off like elastic balls. We consider the behavior of such a localized pattern on 1D la...

Introduction Arterial spin labeling is sensitive to contamination due to off-resonance effects of the RF label. While it has been argued that in PASL these effects are small compared to pulse profile effects [1], this assessment has to be re-evaluated in view of the advent of highly selective gradient-modulated adiabatic pulses such as FOCI [2], requiring several times more RF energy than the c...