background: molecular diversity of leishmania major and its morphological changes have become a controversial issue among researchers. some aspects of polymorphic shapes of amastigotes in clinical manifestations along with molecular variation were evaluated among suspected patients of some exceptional zoonotic cutaneous leishmaniasis locations in northern khuzestan, southwestern iran. methods: ...

essential hypertension (eh) accounts for 90-95% of hypertension cases. eh, as a progressive cardiovascular syndrome arising from complex and interrelated etiologies, results from combined and interactive effects of genetic and environmental factors. the objective was to investigate the ace i/d and gnb3 c825t polymorphisms and both genotypes combined with seeking gene-gene interactions to furthe...

objective(s): foxp3 gene is an x-linked gene that encodes foxp3 protein, an essential transcription factor in cd4+cd25+foxp3+ regulatory t (treg) cells.  we aimed, in the present study, to investigate the association of two foxp3 polymorphisms, -2383 c/t (rs3761549) and ivs9+459 t/c (rs2280883), with lung cancer. materials and methods:  in a case-control study we analyzed genotypes and alleles ...

present investigation was carried out to identify dna polymorphism of il-2rγ and chb6 genes. sixty five birds belonging to the indigenous chicken of himachal pradesh were utilized. good quality dna samples were subjected to pcr-rflp analysis using chicken specific primers. overnight restriction enzyme digestion was carried out at 37°c with iu hph i and pvu ii for il-2rγ and chb6 genes, respecti...

canine distemper virus (cdv) creates a very contagious viral multi-systemic canine distemper (cd) disease that affects most species of carnivora order. the virus is genetically heterogeneous, particularly in section of the hemagglutinin (h) gene. sequence analysis of the h gene can be useful to investigate distinction of various lineages related to geographical distribution and cdv molecular ep...

objective: aflatoxin is important in the food industry, in animal husbandry and the medical area; there are enormous negative economic impacts due to this toxin. numerous studies have researched extracts and plant compounds with the intent to reduce the growth of aflatoxin-producing organisms, inhibit toxin production and suppress the major toxin encoded genes (i.e., aflr) in these organisms. l...

abstract: fifteen non-aflatoxigenic strains of aspergillus flavus, represent a wide range of geographic regions of iran (six provinces include fars, ardebil, guilan, golestan, kerman and semnan) and vegetative compatibility groups (vcgs), were collected from corn (zea mays l.), peanut (arachis hypogaea l.) and pistachio (pistachia vera l.) soils and kernels, were screened for the presence of af...

it is now agreed that 10-25% of infertile men with azoospermia have submicroscopic deletions of the y chromosome long ann (yq), consistent with the proposed location of the azoospermia locus (azf) in yq 11.23. however, it is not known whether yq microdeletions are unique to men with azoospermia or whether they are also observed in infertile men with less severe defects of spermatogenesis (oligo...

background & objective: streptococcosis is one of the bacterial infections in fish, especially rainbow trout which infects brain and nervous systems of fish and is caused by s. iniae . estimation of the impact of disease prevalence by s. iniae in fish farming in some countries is reported about 100 million dollars per year. some of the most effective proteins in pathogenicity of these bacteria ...

the ovine melatonin receptor 1a (mtnr1a) and aromatase (cyp19) genes were structurally characterized and the association between their variants and reproductive and growth traits was studied in kurdi sheep at kurdi sheep breeding station located in shirvan, iran. the genomic dna was extracted by guanidine thiocyanate-silica gel method. polymerase chain reaction was carried out to amplify 824 bp...