نتایج جستجو برای: pvax1

تعداد نتایج: 64  

2015
Fatemeh Farshadpour Manoochehr Makvandi Reza Taherkhani

BACKGROUND Hepatitis E Virus (HEV) is the causative agent of enterically transmitted acute hepatitis and has high mortality rate of up to 30% among pregnant women. Therefore, development of a novel vaccine is a desirable goal. OBJECTIVES The aim of this study was to construct tPAsp-PADRE-truncated open reading frame 2 (ORF2) and truncated ORF2 DNA plasmid, which can assist future studies with...

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2013
Olga Krotova Elizaveta Starodubova Stefan Petkov Linda Kostic Julia Agapkina David Hallengärd Alecia Viklund Oleg Latyshev Eva Gelius Tomas Dillenbeck Vadim Karpov Marina Gottikh Igor M. Belyakov Vladimir Lukashov Maria G. Isaguliants

Our objective is to create gene immunogens targeted against drug-resistant HIV-1, focusing on HIV-1 enzymes as critical components in viral replication and drug resistance. Consensus-based gene vaccines are specifically fit for variable pathogens such as HIV-1 and have many advantages over viral genes and their expression-optimized variants. With this in mind, we designed the consensus integras...

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Journal: :jundishapur journal of microbiology 0
fatemeh farshadpour department of microbiology and parasitology, school of medicine, bushehr university of medical sciences, bushehr, ir iran; health research institute, infectious and tropical disease research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran manoochehr makvandi health research institute, infectious and tropical disease research center, ahvaz jundishapur university of medical sciences, ahvaz, ir iran reza taherkhani department of microbiology and parasitology, school of medicine, bushehr university of medical sciences, bushehr, ir iran; persian gulf tropical medicine research center, bushehr university of medical sciences, bushehr, ir iran; department of microbiology, school of medicine, bushehr university of medical sciences, moallem st., bushehr, ir iran. tel: +98-9171712653, fax: +98-77125220814

conclusions the results of this study demonstrated that the tpasp-padre-truncated orf2 gene cassette and the truncated orf2 gene in recombinant plasmids are successfully expressed in eukaryotic cells. the immunogenicity of the two recombinant plasmids with different formulations will be evaluated as a novel dna vaccine in future investigations. results sequence analysis and bioinformatics studi...

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ژورنال: :genetics in the 3rd millennium 0
سمیه رئیسی somayeh reiisi حشمت شاهی heshmat shahi محمد حسین صنعتی mohammad hossein sanati

بیماری مالتیپل اسکلروزیس (ms) یک بیماری خودایمن مربوط به دستگاه عصبی مرکزی است و سوئ عملکرد دستگاه سیستم ایمنی در آن سبب دمیلینه شدن عصب و ناتوانی نورولوژیکی پیشرونده می شود. برای درمان بیماری از روش های ضد التهابی وحفاظتی استفاده می شود. با این وجود استراتژی های حفاظتی دربیماری به خوبی شناخته نشده اند و استفاده از روش های ضد التهابی به صورت سیستمیک هم به دلیل وجود سد خونی مغزی اثربخشی مناسبی ن...

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