Pyoderma gangrenosum is a rare but significant cause of ulcerations. It is a diagnosis of exclusion. Herein, we suggest diagnostic criteria and some historical perspectives on the diagnosis of pyoderma gangrenosum.

Pyostomatitis vegetans (PV) is a rare condition characterized by pustules that affect the oral mucosa. It is a highly specific marker for inflammatory bowel disease and its correct recognition may lead to the diagnosis of ulcerative colitis or Crohn's disease. Thus, a presumptive diagnosis of PV should suggest a complete gastrointestinal investigation. PV pathogenesis is as yet unknown, althoug...

Pyoderma gangrenosum is characterized by a chronic, non-infectious, destructive ulcer which is mostly seen on distal lower extremities, but it can be found anywhere on body. We report an 18-year old man who developed keloids after healing of his ulcers. He was a known case of chronic relapsing pyoderma gangrenosum. His previous ulcers were used to heal leaving atrophic, cigarette-paper sc...

1. Gonzalez-Moreno J, Ruiz-Ruigomez M, Callejas Rubio JL, et al. Pyoderma gangrenosum and systemic lupus erythematosus: a report of five cases and review of the literature. Lupus 2015;24:130-7. 2. Schoemann MB, Zenn MR. Pyoderma gangrenosum following free transverse rectus abdominis myocutaneous breast reconstruction: a case report. Ann Plast Surg 2010;64:151-4. 3. Tuffaha SH, Sarhane KA, Mundi...