In the title compound, C(11)H(15)N(3) (2+)·2NO(3) (-), one of the imidazole N atoms and the N atom of the pyrrolidine ring are protonated. The pyrrolidine ring adopts an envelope conformation, with the C atom carrying the benzoimidazolium substituent as the flap atom. In the crystal structure, cations and anions are linked through N-H⋯O hydrogen bonds, forming chains that run parallel to the c ...

In the title compound, C20H21NO2, the pyrrolidine ring adopts an envelope conformation with the N atom at the flap position. The central benzene ring makes dihedral angles of 21.39 (10) and 80.10 (15)° with the phenyl ring and the mean plane of the pyrrolidine ring, respectively. The mol-ecular conformation is stabilized by an intra-molecular O-H⋯N hydrogen bond, which closes an S(6) ring. A we...

The title compound, C(21)H(21)NO(2)·C(3)H(7)NO, was synthesized by solvent-free one-pot three-component reaction of naphthalen-2-ol, 2-hy-droxy-benzaldehyde and pyrrolidine. The dihedral angle between the naphthalene ring system and the benzene ring is 77.74 (6)°. The pyrrolidine ring assumes an envelope conformation. An intra-molecular O-H⋯N and an inter-molecular O-H⋯O hydrogen bond are obser...

www.experimentjournal.com 1254 Synthesis, biological activity and docking studies of N,N'-(3S,4S)bis(3,4-disubstituted pyrrolidine)-1-sulfonamide derivatives as β-gluscosidase inhibitors Abstract Starting with L-tartaric acid the chiral 3,4-disubstituted pyrrolidine analogue sulfonamide derivatives were prepared. These compounds were examined for anti-bacterial and anti-fungal activity. Further...

Four stereoisomers of oxy-peptide nucleic acids containing ether linkages in the main chain and conformationally-restricted pyrrolidine rings (pyrrolidine-based oxy-PNA = POPNA) were newly synthesized and investigated for binding to DNA. cis-l-POPNA with 9 adenine bases formed the most stable hybrid with dT(9). The POPNA showed high sequence specificity similar to that of the Nielsen-type PNA a...

The title compound, C21H21NO, is a vinyl-ogous amide (enaminone) produced by reaction of 1-(2-phenyl-prop-2-en-1-yl)pyrrolidine-2-thione with phenacyl bromide. In the mol-ecule, the phenyl rings are twisted from the mean plane of the pyrrolidine ring by 11.2 (1) and 67.3 (1)°. In the crystal, weak C-H⋯O hydrogen bonds link the mol-ecules related by translation along the b axis into chains.

The title compound, C(24)H(26)N(2)O(8), was synthesized by the cyclo-addition reaction of methyl 2-phenyl-acrylate, diethyl 2-amino-malonate and 4-nitro-benzaldehyde. The pyrrolidine ring exhibits an envelope conformation. The two benzene rings are located on opposite sides of the pyrrolidine ring and subtend a dihedral angle of 59.16 (14)°. The crystal packing is stabilized by N-H⋯O and weak C...