Domain wall (DW) pinning in ferromagnetic nanowires is in general a complex process. Distortions of the DW shape make quantitative agreement between modeling and experiment difficult. Here we demonstrate pinning using nanometer scale localized stray fields. This type of interaction gives well-characterized, tailorable potential landscapes that do not appreciably distort the DW. Our experimental...

Expression of imprinted genes is classically associated with differential methylation of specific CpG-rich DNA regions (DMRs). The H19/IGF2 locus is considered a paradigm for epigenetic regulation. In mice, as in humans, the essential H19 DMR--target of the CTCF insulator--is located between the two genes. Here, we performed a pyrosequencing-based quantitative analysis of its CpG methylation in...

We present a near-infrared extinction study of the dark globule B335, a protostellar collapse candidate, using data from HST/NICMOS and the W.M. Keck Observatory. These data allow a new quantitative test of the “inside-out” collapse model previously proposed to explain molecular line profiles observed toward this region. We find that the shape of the density profile is well matched by the colla...

Gap junctions are intercellular channels that link the cytoplasm of neighboring cells. Because a gap junction channel is composed of two connexons docking head-to-head with each other, the channel voltage-gating profile is symmetrical for homotypic channels made of two identical connexons (hemichannels) and asymmetric for the heterotypic channels made of two different connexons (i.e., different...

precision forging process is widely used for the production of spur gears due to its advantages such asimproved strength and surface finish, little waste of materials and reduction in the machining time ofthe gear. an important aspect of precision forging process is the load required to perform the processsuccessfully and design the forging tools. in this research, a new kinematically admissibl...