Jennifer Vines This is the fi rst of 12 Correspondence pieces in this issue that are in response to an important PLoS Medicine Research Article: Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, et al. (2005) Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 trial. PLoS Med 2(11): e298. Readers wishing to add their own ...

Jennifer Vines This is the fi rst of 12 Correspondence pieces in this issue that are in response to an important PLoS Medicine Research Article: Auvert B, Taljaard D, Lagarde E, Sobngwi-Tambekou J, Sitta R, et al. (2005) Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: The ANRS 1265 trial. PLoS Med 2(11): e298. Readers wishing to add their own ...

BACKGROUND Fatigue is one of many unintended consequences of shift work in the nursing profession. Natural health products (NHPs) for fatigue are becoming an increasingly popular topic of clinical study; one such NHP is Rhodiola rosea. A well-designed, rigorously conducted randomized controlled trial is required before therapeutic claims for this product can be made. OBJECTIVE To compare the ...

2681 prednisone after emergency treatment of chronic obstructive pulmonary disease. N Engl J Med 2003;348:2618-25. 12. Snow V, Lascher S, Mottur-Pilson C. The evidence base for management of acute exacerbations of COPD: clinical practice guideline. Chest 2001;119:1185-9. 13. Callahan CM, Dittus RS, Katz BP. Oral corticosteroid therapy for patients with stable chronic obstructive pulmonary disea...

background:  the primary aim of this study was to determine predictors of missed research appointments in a prospective  andomized placebo injection-controlled trial with evaluations 1 to 3 and 5 to 8 months after enrollment.   methods:  this study represents a secondary use of data from 104 patients that were enrolled in a prospective randomized  ontrolled trial of dexamethasone versus lidocai...

conclusions this preliminary assessment suggests that duloxetine may be a medication of interest in the treatment of children with adhd. further controlled studies with larger samples are required to evaluate the efficacy of duloxetine in treatment of children with adhd. results ten children with a mean age of 8.40 ± 1.67 years terminated the trial. a significant reduction in cprs-r and its sub...

In March 2010, Orexigen(R) Therapeutics submitted a new drug application (NDA) for approval of naltrexone sustained release (SR)/bupropion SR (Contrave(R)) for the treatment of obesity in the US. The tablet contains naltrexone SR 32 mg and bupropion SR 360 mg. The drug has been tested in four randomized, double-blind, placebo-controlled, phase III trials and the co-primary endpoints were met in...

2. Davis GL, Esteban-Mur R, Rustgi V, Hoefs J, Gordon S, Trepo C, Shiffman M, Zeuzem S, Craxi A, Raffanel C, Reindollar R, Rizzetto M, International Hepatitis Interventional Therapy Group: Retreatment of relapser after interferon therapy for chronic hepatitis C: An international randomized controlled trial of interferon plus ribavirin VS interferon alone. Hepatology 26:247A, 1997 (abstr) 3. Fer...

Context The RESTORE programme comprises a randomised controlled trial, three pilot trials, a cohort study, qualitative studies and systematic reviews. Since 2010, the patient panel (PEP-R), has inputted into RESTORE. Seventeen patients have been involved in total, 8 were recruited at the time of the evaluation. Through facilitated group sessions, PEP-R provides input into refinement of patient ...