A systematic review of qualitative peer-reviewed publications was conducted to identify drivers of and barriers to help-seeking behaviour in adults with new-onset rheumatoid arthritis (RA). 1058 abstracts were searched to identify relevant publications. 21 relevant publications were identified assessed for quality and subjected to analysis informed by thematic and grounded theory frameworks. Se...

BACKGROUND Suppression of the immunoinflammatory cascade by targeting interleukin 6 (IL-6) mediated effects constitutes a therapeutic option for chronic inflammatory diseases. Tocilizumab is the only IL-6 inhibitor (IL-6i) licensed for rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA), but also other agents targeting either IL-6 or its receptor are investigated in various indica...

OBJECTIVES To perform a systematic literature review of effective strategies for the treatment of rheumatoid arthritis (RA). METHODS As part of a European League Against Rheumatism (EULAR) Task Force investigation, a literature search was carried out from January 1962 until February 2009 in PubMed/Ovid Embase/Cochrane and EULAR/American College of Rheumatism (ACR)) abstracts (2007/2008) for s...

The development of automated methods for revealing the repetitive structure of a given music recording is of central importance in music information retrieval. In this paper, we present a novel scape plot representation that allows for visualizing repetitive structures of the entire music recording in a hierarchical, compact, and intuitive way. In a scape plot, each point corresponds to an audi...

The title compound, C(8)H(18)N(4)O(2) (2+)·2Cl(-), contains two oxime groups. The methyl oxime group has a Z configuration, and the ethyl oxime group is disordered, with both Z and E configurations in occupancies of 0.840 (8) and 0.160 (8), respectively. In the crystal structure, there are a number of N-H⋯Cl hydrogen bonds.

Modified tau is a parameter computed by ACAS to estimate the earliest time at which a collision could occur should an intruder aircraft accelerate toward the own aircraft. A concern with the modified tau calculation has been raised in a class of encounters where intruders are already close and converging slowly. In these problem cases, ACAS may induce a Near Mid-Air Collision by generating RAs ...

Background: Long-term treatment of rheumatoid arthritis (RA) with prednisolone (PRED) is associated with bone mineral density (BMD) loss. This study aimed to determine the status of BMD in non-compliant women who used PRED alone for RA. Methods: Non-adherent RA taking < 7.5 mg daily PRED without DMARDs for > 6 months, and RA patients taking methotrexate +PRED (RA control) were compared with ag...

introduction: commitment to abstracting standards has a very significant role in information retrieval. the present research aimed to evaluate the rate of commitment to iso 214 standards among the persian abstracts of approved research projects at school of health management and medical informatics, isfahan university of medical sciences, isfahan, iran.    methods: this descriptive study used a...