نتایج جستجو برای: radioprotection

تعداد نتایج: 740  

Journal: :In vivo 2010
Michael W Epperly Julie P Goff Song Li Xiang Gao Peter Wipf Tracy Dixon Hong Wang Darcy Franicola Hongmei Shen Jean-Claude M Rwigema Valerian Kagan Mark Bernard Joel S Greenberger

BACKGROUND/AIM this study evaluated esophageal radioprotection by the Gramicidin S (GS) derived-nitroxide, JP4-039, a mitochondrial targeting peptide-isostere covalently-linked to 4-amino-Tempo, delivered in a novel swallowed oil-based (F15) formulation. MATERIALS AND METHODS C57BL/6HNsd female mice received intraesophageal F15 formulation containing JP4-039 (4 mg/ml in 100 microl volumes) 10...

Journal: :International journal of molecular sciences 2018
Martyna Śniegocka Ewa Podgórska Przemysław M Płonka Martyna Elas Bożena Romanowska-Dixon Małgorzata Szczygieł Michał A Żmijewski Mirosława Cichorek Anna Markiewicz Anna A Brożyna Andrzej T Słominski Krystyna Urbańska

The focus of the present review is to investigate the role of melanin in the radioprotection of melanoma and attempts to sensitize tumors to radiation by inhibiting melanogenesis. Early studies showed radical scavenging, oxygen consumption and adsorption as mechanisms of melanin radioprotection. Experimental models of melanoma in hamsters and in gerbils are described as well as their use in bio...

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