Therapeutic drug monitoring (TDM) is a useful tool for optimising the use of anti-TNFα inhibitors in patients with inflammatory bowel diseases (IBDs). Recently, point-of-care methods quantification levels and anti-drug antibodies (ADAs) have been developed to overcome limitations conventional enzyme-linked immunoabsorbent assays (ELISAs). Here, we evaluated performance, interchangeability, agre...

Reactive intermediate deaminase (Rid) protein family is a recently discovered group of enzymes that is conserved in all domains of life and is proposed to play a role in the detoxification of reactive enamines/imines. UK114, the mammalian member of RidA subfamily, was identified in the early 90s as a component of perchloric acid-soluble extracts from goat liver and exhibited immunomodulatory pr...

In this paper, we study the performance of various IDA*-style searches and investigate methods to improve their performance by predicting in each stage the threshold to be used for pruning. Without loss of generality, we consider minimization problems in this paper. We rst present three models to approximate the distribution of the number of search nodes by lower bounds: exponential, geometric ...

In July 2020, Abdul Rashid Dostum, a former militia leader known for frequently switching sides, was promoted to Marshal – the highest rank in Afghan security forces and that had not bee...

Recommendations for the Treatment of Chronic Hepatitis B infection in children Uzma Shah1, Iqbal Memon2, Huma Arshad Cheema3, Salman Ali4, Sohail Thobani5, Rashid Mirza6 Aga Khan University Hospital1, Dow University of Helath Sciences2, Karachi, Children’s Hospital3, Lahore, Combined Military Hospital4, Rawalpindi, BMI Polyclinic5 Karachi, Mideast Medical Centre, Karachi, Sindh Institute of Uro...

http://www.ayubmed.edu.pk/JAMC/23-1/Mohsin.pdf 1 EDITORIAL GLUTEN-FREE DIET: DEFINITION AND APPLICATIONS Mohsin Rashid, Aamir Ghafoor Khan Medical Advisory Board, Pakistani Celiac Society, Lahore, Pakistan Division of Gastroenterology and Nutrition, Department of Paediatrics, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada Faculty of Gastroenterology, Post Graduate Medic...