Both aging and age-associated neurodegenerative diseases are related with various degrees of behavioral impairments, and among the prime candidates responsible for producing the neuronal changes mediating these behavioral deficits, appear to be free radicals and the oxidative agents which they generate. Free radicals such as vit. E may be important factors in maintaining neuronal integrity and ...

The aim of this work was to study age-related changes in the behaviour adult Wistar rats using open field (OF) and elevated plus maze (EPM) tests. Behavioural related motor activity anxiety were particular interest. Results showed that as male female progressed from 2 5 months age, there a decrease level exploratory activities an increase their anxiety. Age-related dependent upon initial indivi...

objective(s): epilepsy is a neurodevelopmental disorder which is strongly influenced by genetic and environmental factors. gestational stress has been shown to be an important factor for affecting seizure susceptibility. the present study was conducted to address whether gestational stress may affect pentylentetrazol (ptz)-induced epileptic behavior in rat offspring in a sex- and age- dependent...