We propose a new chemical detection technique in which an analyte's vibrational frequencies are interrogated directly using an array of nanomechanical resonators. This "nanomechanical resonance spectroscopy" (NRS) could permit label-free chemical detection, combining the high sensitivity of nanomechanical approaches with the high selectivity of traditional spectroscopy. A computational proof of...

IN PREVIOUS studies [l] it has been established that a cluster of social events requiring change in ongoing life adjustment is significantly associated with the time of illness onset. Similarly, the relationship of what has been called ‘life stress,’ ‘emotional stress,’ ‘object loss,’ etc. and illness onset has been demonstrated by other investigations [2-131. It has been adduced from these stu...

Objective: To develop and test the reliability and validity of the State Behavioral Scale for use in describing sedation/agitation levels in young intubated patients supported on mechanical ventilation. Design: In this prospective, psychometric evaluation, pairs of trained pediatric critical care nurse evaluators simultaneously and independently assessed a convenience sample of pediatric intens...

BACKGROUND Numerical rating scales (NRS), and verbal rating scales (VRS) showed to be reliable and valid tools for subjective cancer pain measurement, but no one of them consistently proved to be superior to the other. Aim of the present study is to compare NRS and VRS performance in assessing breakthrough or episodic pain (BP-EP) exacerbations. METHODS In a cross sectional multicentre study ...

In the summer of 1997, the Air Traffic Selection and Training (AT-SAT) High Fidelity Simulation Study was conducted at the FAA Academy in Oklahoma City, OK. The purpose of the study was to test the performance of 107 operational en route controllers during 2½ days of simulations. The performance of these controllers during the high-fidelity simulations was compared with their performance on two...

Tonsillectomy is one of the most common surgical procedures for otolaryngologists. Although tonsillectomy procedures are common, like any surgical procedure, there are post-operative complaints and complications. The aim of this retrospective study was to evaluate the pattern of post-operative pain in tonsillectomy using the harmonic scalpel (HS). 43 patients were entered into this study (13 me...

BACKGROUND There is uncertainty about the efficacy of lamotrigine in bipolar depressive episodes. AIMS To synthesise the evidence for the efficacy of lamotrigine in bipolar depressive episodes. METHOD Systematic review and meta-analysis of individual patient data from randomised controlled trials comparing lamotrigine with placebo. RESULTS Individual data from 1072 participants from five ...