We investigate the simultaneous existence of two centers (bi-center) for two families of planar Z2-equivariant differential systems. First we present necessary and sufficient conditions for the existence of an isochronous bi-center for a planar Z2-equivariant cubic system having two centers at the points (−1, 0) and (1, 0), completing the study done by Liu and Li (2011). Next, we give condition...