Somatic cell nuclear transfer is used to generate genetic models for research and new, genetically modified livestock varieties. Goat fetal fibroblast cells (gFFCs) are the predominant nuclear donors in Cashmere goat transgenic cloning, but have disadvantages. We evaluated the potential of goat adipose-derived mesenchymal stem cells (gADSCs) and goat skeletal muscle-derived satellite cells (gMD...

The expression of retinoid-acid-related orphan receptor α (RORα) was evaluated at the mRNA level using real-time polymerase chain reaction (qRT-PCR), and its expression localization was determined by in situ hybridization of adult Inner Mongolian cashmere goats at different times of the year. In situ hybridization demonstrated that RORαwas expressed in secondary hair follicles of the hair shaft...

OINCE its domestication the goat has served man well. As a source of milk, meat, mohair, and skins it has furnished him both food and clothing, and because of its brush-eating proclivities, has spared him untold amounts of hard labor with the brush hook. Since 1900 the Angora goat industry in the United States has undergone rapid expansion. At present it is confined largely to the Southwestern ...

A previous whole-genome association analysis identified lysine demethylase 6A (KDM6A), which encodes a type of histone demethylase, as a candidate gene associated to goat fecundity. KDM6A gene knockout mouse disrupts gametophyte development, suggesting that it has a critical role in reproduction. In this study, goat KDM6A mRNA expression profiles were determined, insertion/deletion (indel) vari...

Insulin-like growth factor-binding protein-5 (IGFBP-5) is one of the six members of IGFBP family, important for cell growth, apoptosis and other IGF-stimulated signaling pathways. In order to explore the significance of IGFBP-5 in cells of the Inner Mongolian Cashmere goat (Capra hircus), IGFBP-5 gene complementary DNA (cDNA) was amplified by reverse transcription polymerase chain reaction (RT-...

A trial was conducted to investigate the potential of the progeny of feral goats x selected, cashmere producing, bucks to utilize high levels of supplementary protein in order to increase cashmere yield. A basal diet (approx. 10 per cent crude protein (CP) and 12 MJ metabolisable energy (ME)) was fed on its own or supplemented in the following ways: urea (1.5 per cent), fishmeal (5, 10 and 15 p...