نتایج جستجو برای: rb51 brucella abortus

تعداد نتایج: 6828  

Journal: :MMWR. Morbidity and mortality weekly report 2008

In November 2007, New York State Department of Health (NYSDOH) officials notified CDC of potential exposures to attenuated vaccine strain Brucella abortus RB51 (RB51) in multiple clinical laboratories that participated in a Laboratory Preparedness Survey (LPS) proficiency test. NYSDOH conducted a survey of participating laboratories and identified 17 laboratories that reported handling the RB51...

Journal: :Infection and immunity 2002
Jinkyung Ko Annette Gendron-Fitzpatrick Thomas A Ficht Gary A Splitter

Interferon regulatory factor 1-deficient (IRF-1(-/-)) mice infected with virulent Brucella abortus 2308 at 5 x 10(5) CFU developed acute hepatitis similar to many natural hosts but, unlike natural hosts, IRF-1(-/-) mice were unable to resolve infection and died. In contrast, IRF-1(-/-) mice survived when infected at 5 x 10(5) CFU with several attenuated Brucella strains (S19, RB51, cbp, and cyd...

Journal: :Infection and immunity 2007
Paola Caro-Hernández Luis Fernández-Lago María-Jesús de Miguel Ana I Martín-Martín Axel Cloeckaert María-Jesús Grilló Nieves Vizcaíno

The genes coding for the five outer membrane proteins (OMPs) of the Omp25/Omp31 family expected to be located in the outer membrane (OM) of rough virulent Brucella ovis PA were inactivated to evaluate their role in virulence and OM properties. The OM properties of the mutant strains and of the mutants complemented with the corresponding wild-type genes were analyzed, in comparison with the pare...

Journal: :Infection and immunity 2003
Bruno Rouot Maria-Teresa Alvarez-Martinez Carine Marius Pierrette Menanteau Laurence Guilloteau Rose-Anne Boigegrain Robert Zumbihl David O'Callaghan Natalie Domke Christian Baron

Expression of the virB operon, encoding the type IV secretion system required for Brucella suis virulence, occurred in the acidic phagocytic vacuoles of macrophages and could be induced in minimal medium at acidic pH values. To analyze the production of VirB proteins, polyclonal antisera against B. suis VirB5 and VirB8 were generated. Western blot analysis revealed that VirB5 and VirB8 were det...

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