This paper proposes a novel idea of reversible contrast enhancement (RCE) for digital images. Different from the traditional methods, we aim to embed the reversible feature into image contrast enhancement, making sure that the processed image can be losslessly turned back to the original. The original image is enhanced by histogram shrink and contrast stretching. Meanwhile, side information is ...

In this paper we analyze theoretically the ‘‘signal background’’ observed in experimental studies of the radiative decay of hydrogen atoms following resonant coherent excitation ~RCE! in grazing collisions with a LiF surface. The radiation intensity is evaluated by treating the RCE within a time-dependent ~classicaltrajectory! quantal approach, and by assuming that the excited electronic states...

Objetivou-se investigar a frequência de fatores risco cardiovascular (FRCV) e complicações cardiovasculares em adultos hipertensos Maceió-AL, com dados dois estudos transversais (2007/2009 2013/2016). Analisou-se FRCV: tabagismo, sedentarismo, antecedentes familiares, baixa estatura, sobrepeso/obesidade (SBP/OB), obesidade (OB), razão cintura/estatura (RCE), índice conicidade (IC) abdominal (OA...

BACKGROUND AND PURPOSE The current gold standard for imaging intracranial AVMs involves catheter-based techniques, namely cerebral digital subtraction angiography (DSA). However, DSA presents some procedural risks to the patient. Unfortunately, AVM patients usually undergo multiple DSA exams throughout their diagnostic and therapeutic course, significantly increasing their procedural risk expos...

Enzyme-prodrug approaches to cancer therapy, theoretically, have the potential to mediate tumor-selective cytotoxicity. However, even if tumor-specific prodrug activation is achieved, enzyme-prodrug systems investigated thus far comprised a single enzyme and a specific prodrug. Although targeted, such systems constitute single-agent therapy, which may be ineffective and/or may promote developme...

7-Ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecin (irinotecan, CPT-11) is a camptothecin prodrug that is metabolized by carboxylesterases (CE) to the active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38), a topoisomerase I inhibitor. CPT-11 has shown encouraging antitumor activity against a broad spectrum of tumor types in early clinical trials, but hematopoietic and gastroin...

Metabolic research for herbal medicine (HM) is a formidable task, which is still in its infancy due to complicated components in HM, complex metabolic pathways, and lack of authentic standards. The present work contributes to the development of a powerful technical platform to rapidly identify and classify metabolites of herbal components based on a liquid chromatography hybrid ion trap time-of...

We wanted to determine whether cell populations and soluble components in bronchoalveolar lavage (BAL) could be useful in predicting the outcome of lung function and chest radiography in patients with untreated pulmonary sarcoidosis. Analysis of soluble proteins in BAL fluid, included the levels of immunoglobulins and the two major antiproteases, alpha 2-macroglobulin (alpha 2-M) and alpha 1-pr...