Hydroperoxide lyase, 1 l-Formyl-c/5-9-undecenoie Acid, 180-Labeled 13-L-Hydroperoxylinoleic acid, Oxygen-Isotope Effect Hydroperoxide lyase E" solubilized with Tween 20 from tea chloroplasts was shown to catalyze cleavage reaction of 13-L-hydroperoxy-cz'j-9,fra/w-11-octadecadienoic acid (13-L-hydroperoxylinoleic acid) to hexanal, a CB-compound and 1 l-form yl-m -9-undecenoic acid, a C12-compoun...

Carbonyl sulfide (OCS) is an abundant sulfur (S)-bearing species in the interstellar medium. It present not only gas phase, but also on grains as a solid; therefore, OCS very likely undergoes physicochemical processes icy surfaces at low temperatures. The study experimentally and computationally investigates reaction of solid with hydrogen (H) atoms amorphous water results show that addition H ...

During the last decade, gold-catalyzed reactions have become a tour de force in organic synthesis. Recently, the gold-, Brønsted acid- or Lewis acid-catalyzed oxygen transfer from carbonyl to carbon-carbon triple bond, the so-called alkyne-carbonyl metathesis, has attracted much attention because this atom economical transformation generates α,β-unsaturated carbonyl derivatives which are of gre...

Inducing high levels of reactive oxygen species (ROS) inside tumor cells is a cancer therapy method termed chemodynamic (CDT). Relying on delivery Fenton reaction promoters such as Fe2+, CDT takes advantage overproduced ROS in the microenvironment. We developed peptide-H2S donor conjugate, complexed with AAN-PTC–Fe2+. The AAN tripeptide was specifically cleaved by legumain, an enzyme overexpres...

para-aminobenzoic acid is supported on silica gel via reaction of activated silica gel and p-aminobenzoic acid which is then converted to its manganese and cobalt salts. a mixture of the manganese and cobalt salts of the acid is used to catalyze allylic and benzylic alcohols to their corresponding carbonyl compounds in reasonable yields using oxygen or air. reactions are clean and the catalysts...

The complex of porcine pancreatic elastase (PPE) with 7-amino-3-(2-bromoethoxy)-4-chloroisocoumarin, a potent mechanism-based inhibitor, was crystallized and the crystal structure determined at 1.9-A resolution with a final R factor of 17.1%. The unbiased difference Fourier electron density map showed continuous density from O gamma of Ser 195 to the benzoyl carbonyl carbon atom and from N epsi...

Methylmalonyl-CoA mutase is an adenosylcobalamin-dependent enzyme that catalyzes the 1,2 rearrangement of methylmalonyl-CoA to succinyl-CoA. This reaction results in the interchange of a carbonyl-CoA group and a hydrogen atom on vicinal carbons. The crystal structure of the enzyme reveals the presence of an aromatic cluster of residues in the active site that includes His-244, Tyr-243, and Tyr-...