background: increased serum high sensitive c-reactive protein (hs-crp) in asthma and its association with disease severity has been investigated in many studies. this study aimed to determine serum hs-crp status in asthma versus healthy controls and to examine its ability in predicting asthma control. methods: serum crp was measured by elisa method using a high sensitive crp kit. severity of as...

introduction : surgical removal of inferior third molar tooth is associated with post-operative complications such as pain, trismus and edema. decreasing the post-operative inflammation and edema is one of the important goals in drug administration. for management of post-operative pain, nonsteroidal anti-inflammatory drugs (nsaids) and opioids can be administered. c-reactive protein (crp) is o...

background & objective: there are many common infections and inflammations among people over the world. this demands an affordable and reliable test with high sensitivity/specificity to predict or confirm the diagnosis of such cases in routinely clinical practice. in the present study, we aimed to find any potential correlation between serum levels of ggt and crp- q and/or hs- crp and wbc c...

coronary heart disease is the leading cause of death and disability in adults. the association between acute coronary syndrom (acs) and elevated serum high sensitivity c-reactive protein (hscrp) suggests that chronic inflammation of the coronary arterial wall may play an important role. a number of drugs used in the treatment of cardiovascular disease reduce serum crp. it* is therefore possible...

Objective(s): Diabetes mellitus has been suggested to be the most common metabolic disorder associated with magnesium deficiency. This study aimed to investigate the effects and mechanisms of magnesium supplementation on insulin receptor activity in elderly type 2 diabetes using a rat model and to provide experimental evidence for insulin resistance improvement by magn...

the antidiuretic effect of arginine vasopressin (avp) is mediated by the vasopressin v2 receptor. the docking study of avp as a ligand to v2 receptor helps in identifying important amino acid residues that might be involved in avp binding for predicting the lowest free energy state of the protein complex. whereas previous researchers were not able to detect the exact site of the ligand-receptor...

A growing body of evidence suggests that GPCRs exist and function as dimers or higher oligomers. The evidence for GPCR dimerization comes from biochemical, biophysical and functional studies. In addition, researchers have shown the occurrence of heterodimerization between different members of the GPCR family. Two receptors can interact with each other to make a dimer through their extracellular...

Background: Malignant melanoma is the most aggressive form of skin cancer. In contrast to other tumors, the role of estrogen in the initiation and progression of melanoma remains unclear. The aim of this study was to evaluate estrogen receptor beta protein expression in human melanoma tissues and in the benign melanocytic lesions. Method: Twenty-one patients, 11 with cutaneous melanoma and 10 w...