OBJECTIVE To determine the comparative efficacy of oral itraconazole versus intravaginal clotrimazole in suppressing recurrent episodes of vulvovaginal candidiasis. DESIGN Prospective randomised open study of women with recurrent vulvovaginal candidiasis. Clinical and microbiological assessments were made monthly for 12 months. SETTING Women's Clinic of a University teaching hospital. SUB...

OBJECTIVE Mucosal infections including vulvovaginal candidiasis are a common problem for women with human immunodeficiency virus (HIV) infection. Our objective was to determine which factors predict the development of symptomatic disease among HIV-infected women. MATERIALS AND METHODS In a prospective study from 1991 to 1995, 205 HIV-positive women were evaluated every 6 months for occurrence...

OBJECTIVES To present sales figures of antifungal drugs for treatment of genital Candida infections in females, which had been purchased in the Swedish county of Skåne (with approximately 1.2 million inhabitants) during the 1990s. To study the relative proportions of the drugs sold by prescription and as over-the-counter (OTC) products. METHODS Sales figures of antifungal drugs for therapy of...

BACKGROUND Vulvovaginal Candidiasis (VVC) is a frequent, complex and cumbersome condition that can cause physical and psychological distress for the involved individual. Candida albicans was reported as the most common agent of VVC yet it seems that we are recently encountering changes in the pattern of Candida species in VVC. OBJECTIVES In this study we assessed different species of Candida ...

The incidence and prevalence of fungal infections in Russia is unknown. We estimated the burden of fungal infections in Russia according to the methodology of the LIFE program (www.LIFE-worldwide.org). The total number of patients with serious and chronic mycoses in Russia in 2011 was three million. Most of these patients (2,607,494) had superficial fungal infections (recurrent vulvovaginal can...

the aim of the present study was to investigate the antifungal activity of zatariamultiflora essential oil, fluconazole and ciclopirox olamine against 44 non-albicanscandida isolates from patients with recurrent vulvovaginal candidiasis. a set of c.glabrata (29 strains), c. krusei (3 stains) and c. patapsilosis (2 strains) were studiedusing clinical and laboratory standards institute (clsi) bro...

OBJECTIVE Although recurrent vulvovaginal candidiasis is defined as 4 or more discrete attacks of vulvovaginal candidiasis per year, there is no diagnostic nomenclature or definition for the many women who are chronically symptomatic. This study aims to establish and propose a definition and a set of diagnostic criteria, which would enable clinicians to promptly identify and treat women with ch...