Redox reactions are at the heart of bioenergetics, yet their biological role is not restricted to metabolism. One specific focus of contemporary Redox Biology is the study of how the folding, stability, activity, and interactivity of proteins are subject to redox control. Key questions pertain to the chemical nature of physiological redox changes and their exact location inside the cell, the na...

The notion that electrophiles serve as messengers in cell signaling is now widely accepted. Nonetheless, major issues restrain acceptance of redox homeostasis and redox signaling as components of maintenance of a normal physiological steady state. The first is that redox signaling requires sudden switching on of oxidant production and bypassing of antioxidant mechanisms rather than a continuous...

Myeloperoxidase, eosinophil peroxidase and lactoperoxidase are heme-containing oxidoreductases, which undergo a series of redox reactions. Though sharing functional and structural homology, reflecting their phylogenetic origin, differences are observed regarding their spectral features, substrate specificities, redox properties and kinetics of interconversion of the relevant redox intermediates...

ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 complex was prepared according to literature report. the reaction between aforementioned complex via sodium alkoxides as a reactants, were carried out in the solid state. the [ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 undergoes an intramolecular two electrons oxidation-reduction reaction at room temperature and metallic nickel nanoparticles (ni1-ni5) was ...

ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 complex was prepared according to literature report. the reaction between aforementioned complex via sodium alkoxides as a reactants, were carried out in the solid state. the [ni6(n2h4)6(so4)4(oh)2(h2o)8](so4)(h2o)10 undergoes an intramolecular two electrons oxidation-reduction reaction at room temperature and metallic nickel nanoparticles (ni1-ni5) was ...

Roll over transition metals-triarylamines are redox-catalysts, enabling olefin difunctionalization and C–H functionalization reactions by activating benzoyl peroxide.

Mammalian cells do not survive in the absence of redox reactions; oxidation and reduction predominate in the swamp of metabolic biochemical reactions inside the cell. In a situation which is less stoichiometric, subtle alterations of the redox status in the intracellular environment also have significant impacts on cell biology. Changes in the intracellular redox status can be assessed by quant...

Redox reactions are central to energy conversion and life metabolism. Herein we present electrochemical measurements with fluorescent readout of the redox-sensitive dye Methylene Blue (MB), at the single-molecule (SM) level. To overcome the low fluorescence quantum yield of MB we enhanced fluorescence by using individual gold nanorods to achieve the required sensitivity. By measuring the same m...

Target audience: Research scientists or clinicians who are interested in cancer metabolism, oxidative stress and redox state. Introduction/Purpose: Cellular redox state has been demonstrated as a key player in cellular biology. The disturbed balance of the redox state, such as excessive oxidative stress, can lead to many pathologic changes including cancer, heart diseases, neurodegenerative dis...