ILs organocatalyzed regioselective hydroboration of alkenes with HBpin provides anti-Markovnikov adducts high yields and selectivity. The system allows catalyst recycling up to 30 runs. Transformations alkylboronic esters are also included.

A Ni-based ternary nanocomposite, Ni–rGO–zeolite, has been developed as an efficient and recyclable heterogeneous catalyst for on-water regioselective azide alkyne cycloaddition.

Highly regioselective hydroxylation of propane at the terminal position has been achieved using CYP153A33 with decoy molecules. This combination can exhibit ability to hydroxylate ethane and methane.

With fluoroaromatic compounds increasingly employed as scaffolds in agrochemicals and active pharmaceutical ingredients, the development of methods which facilitate regioselective functionalisation their C–H C–F bonds is a frontier...

tert-Butyldimethylsilyl (TBDMS) and tert-butyldiphenylsilyl (TBDPS) are alcohol protecting groups widely employed in organic synthesis in view of their compatibility with a wide range of conditions. Their regioselective installation on polyols generally requires lengthy reactions and the use of high boiling solvents. In the first part of this paper we demonstrate that regioselective silylation ...

A regioselective epoxy alcohol cyclization promoted by the combination of neutral water and a tetrahydropyran template was investigated through a series of mechanistic experiments carried out on an epoxy alcohol containing a tetrahydropyran ring (1a) and its carbocyclic congener (1b). In contrast to 1a, cyclizations of 1b were unselective and displayed significantly faster reaction rates sugges...

An efficient and convenient method was developed for the one-step synthesis of various substituted ethyl 2-(1H-indol-2-yl) acetates via a palladium-catalyzed regioselective cascade C-H activation reaction. Importantly, this practical approach can be carried out with readily accessible starting materials and exhibits excellent functional group compatibility. chemistry, methods for regioselective...

A highly regioselective acylation of myo-inositol 1,3,5-orthoformate at the 4-O/6-O positions is catalyzed by various metal trifluoromethanesulfonates, giving excellent yields; an asymmetric example using (-)-camphanic anhydride is described here.