نتایج جستجو برای: regulatory response

تعداد نتایج: 1130976  

Background: Successful pregnancy in allopregnant women depends upon the control of graft rejection mechanisms. It has been suggested that some immunosuppressive cytokines contribute to successful pregnancy and transplantation. Transforming growth factor beta (TGF-   β) exhibits potent immunoregulatory and anti-inflammatory properties which might prolong graft survival. Recent studies suggest a ...

Journal: :iranian journal of immunology 0
tyebeha hashempoor department of virology, school of medical sciences, tarbiat modares university of medical sciences taravat bamdad department of virology, school of medical sciences, tarbiat modares university of medical sciences shahin merat digestive disease research center, shariati hospital, tehran university of medical sciences ehsan janzamin rooyan institute leila nemati rooyan institute hossain jabbari digestive disease research center, shariati hospital, tehran university of medical sciences amir-houshang sharifi

background: regulatory t cells (tregs) have been involved in impaired immunity and may have a pivotal role in persistence of viral infections. objective: to develop a simple and reliable in-house three color flow cytometery of peripheral blood to understand the role of hcv infection in the increase of tregs. methods: the level of naturally occurring cd4+cd25+foxp3+ regulatory t cells (ntregs) i...

Journal: :Cancer research 2006
Rong-Fu Wang

T regulatory (Treg) cells that suppress immune responses may limit the efficiency of cancer immunotherapy. Recent findings indicate that Toll-like receptors (TLR) directly regulate the suppressive activity of Treg cells. Linking TLR signaling to the functional control of Treg cells may offer new opportunities to improve the outcome of cancer immunotherapy by coadminstration of certain TLR ligands.

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Michael A DiMattia Norman R Watts Stephen J Stahl Christoph Rader Paul T Wingfield David I Stuart Alasdair C Steven Jonathan M Grimes

HIV-1 Rev is a small regulatory protein that mediates the nuclear export of viral mRNAs, an essential step in the HIV replication cycle. In this process Rev oligomerizes in association with a highly structured RNA motif, the Rev response element. Crystallographic studies of Rev have been hampered by the protein's tendency to aggregate, but Rev has now been found to form a stable soluble equimol...

2018
Faizan Ehsan Elahi Ammar Hasan

Gene regulatory networks (GRNs) are quite large and complex. To better understand and analyse GRNs, mathematical models are being employed. Different types of models, such as logical, continuous and stochastic models, can be used to describe GRNs. In this paper, we present a new approach to identify continuous models, because they are more suitable for large number of genes and quantitative ana...

Journal: :The Netherlands journal of medicine 2006
J Damoiseaux

Regulatory T cells seem to represent the resurrection of the old suppressor T cells. Although of a different phenotype, regulatory T cells are able to suppress many T cell mediated immune responses. While most basic knowledge about these cells is derived from animal studies, the recent identification of these cells in humans has further attributed to their characterisation by in vitro analysis....

2015
Guy E. Zinman Shoshana Naiman Dawn M. O'Dee Nishant Kumar Gerard J. Nau Haim Y. Cohen Ziv Bar-Joseph

Identifying conserved and divergent response patterns in gene networks is becoming increasingly important. A common approach is integrating expression information with gene association networks in order to find groups of connected genes that are activated or repressed. In many cases, researchers are also interested in comparisons across species (or conditions). Finding an active sub-network is ...

Journal: :journal of herbal drugs (an international journal on medicinal herbs) 2014
ziba fooladvand bahman fazeli nasab reza derikvand abdolah ghasemi pirbaloti

background & aim: investigation of suspension cell culture and callus production in catharanthus roseus. catharanthus roseus is an herbaceous perennial plant belongs to the family apocynaceae. c. roseus is important as commercial medicinal plant because of its alkaloidal content. whole plant contains about 130 alkaloids those are classified as vinca alkaloids. vincristine and vinblastine; t...

Journal: :iranian biomedical journal 0
محمود اوراضی زاده mahmoud orazizadeh donald m. salter

signal regulatory proteins (sirp) belong to immunoglobulin super family (igsf) and relate to integrin signaling cascades. it has been shown that sirpa is expressed in a variety of cells including myeloid cells and neurons. in the present study the expression of this igsf member in articular chondrocytes was investigated. methods: using a panel of anti-sirpalpha antibodies, immunohistochemistry,...

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