PURPOSE Invasive mechanical ventilation is associated with complications, and its abbreviation is desirable. The imbalance between increased workload, decreased inspiratory muscle strength and endurance is an important determinant of ventilator dependence. Low endurance may be present due to respiratory muscle atrophy, critical illness, or steroid use. Specific inspiratory muscle training may i...

OBJECTIVES This study is conducted to investigate an optimal timing of sequential noninvasive positive pressure ventilation (NPPV) applied for patients with acute exacerbations of chronic obstructive pulmonary disease (AECOPD). PATIENTS AND METHODS Application of NPPV for 102 patients was randomly observed in the conditions of a 2-hour spontaneous breathing trial (SBT-2) and pulmonary infecti...

BACKGROUND AND OBJECTIVES We report a case of pneumothorax caused by a bronchial perforation during a reintubation using an airway exchange catheter (AEC) in a patient with a head and neck cancer. CASE REPORT A 53 year old man with oropharynx carcinoma was admitted to ICU for severe pneumonia and severe acute respiratory distress syndrome (ARDS). The patient was recognized as a difficult-to-i...

OBJECTIVE To assess whether a systematic approach to weaning and extubation (intervention) is superior to the sole physician's judgment (control) in preventing reintubation secondary to extubation failure in patients with neurologic disorders. DESIGN Randomized controlled trial. SETTING Intensive care unit of a large teaching hospital. PATIENTS Three hundred eighteen intubated patients wh...

Background: In recent years, various noninvasive respiratory support (NRS) of ventilation has been provided more in neonates. The aim of this study was to compare the effect of HFNC with NCPAP in post-extubation of preterm infants with RDS after INSURE method (intubation, surfactant, extubation).Methods: A total of 54 preterm infants with RDS (respiratory distress syndrome) were enrolled in thi...

QUESTION Does inspiratory muscle training improve inspiratory muscle strength and endurance, facilitate weaning, improve survival, and reduce the rate of reintubation and tracheostomy in adults receiving mechanical ventilation? DESIGN Systematic review of randomised or quasi-randomised controlled trials. PARTICIPANTS Adults over 16 years of age receiving mechanical ventilation. INTERVENTI...

BACKGROUND AND OBJECTIVE Postextubation problems such as laryngeal edema and reintubation are common complications after tracheal intubation. The cuff-leak test has been proposed as a method of identifying those patients at high risk in clinical practice, but its efficacy remains controversial. METHODS We searched electronic databases including PubMed, the Cochrane Controlled Trials Register,...

BACKGROUND The effects of high flow nasal cannula (HFNC) on adult patients after extubation remain controversial. We aimed to further determine the effectiveness of HFNC in comparison to noninvasive positive pressure ventilation (NIPPV) and conventional oxygen therapy (COT). METHODS The Pubmed, Embase, Medline, Cochrane Central Register of Controlled Trails (CENTRAL) as well as the Informatio...

BACKGROUND AND OBJECTIVES This study compared the rates of acute respiratory failure, reintubation, length of intensive care stay and mortality in patients in whom the non-invasive mechanical ventilation (NIMV) was applied instead of the routine venturi face mask (VM) application after a successful weaning. METHODS Following the approval of the hospital ethics committee, 62 patients who were ...

This study aimed to determine the frequency of prophylactic steroid administration prevent reintubation after extubation in critically ill patients. We systematically searched MEDLINE, Embase and Cochrane Library for studies regarding preventive use multiple doses or single-dose steroids prior on July 2020 conducted a network meta-analysis (NMA) compare these interventions. To assess risk bias ...