نتایج جستجو برای: release efficiency

تعداد نتایج: 594837  

Girish Tripathi, Gopal Nath Satyawan Singh

   Oral pH sensitive drug delivery systems are of utmost importance as these systems deliver the drug at specific part of the gastrointestine (GI) as per the pH of GI, resulting in improved patient therapeutic efficacy and compliance. The pH range of fluids in various segments of the GI tract may provide environmental stimuli for drug release. The aim of this study was to design buoyant beads c...

Journal: :research in pharmaceutical sciences 0
m tabbakhian a sharifian ma shatalebi

preparation of tretinoin-containing microspheres with the aim of reducing undesirable skin reactions towards trans retinoic acid (tra) and thus, improving patient compliance is of particular interest. these microspheres have to be smaller than 30 m m to avoid causing gritty feel when applying on the skin, and slow the release of drug to minimize its skin side effects. following preliminary eval...

Journal: :iranian journal of pharmaceutical research 0
p khazaeli f hassanzadeh

microencapsulation has become a common technique in the production of controlled release dosage forms. many results have been reported, concerning the use of alginate beads as controlled release drug formulations. alginate has a unique gel-forming property in the presence of multivalent cations, in an aqueous medium. ibuprofen is an excellent analgesic and antipyretic, non-steroidal anti-inflam...

Journal: :iranian journal of pharmaceutical research 0
naga sravan kumar varma vegesna jss college of pharmacy, jss university, mysore shivakumar h.g jss univesity balamuralidhara [email protected] jss university navya m jss university umme hani jss university

the aim of the research work was to chemically modify guar gum(gg) as a ph sensitive co-polymer and formulating intestinal targeting eso nanoparticles (nps) using the synthesized co-polymer. poly acrylamide-grafted-guar gum (paam-g-gg) co-polymer was synthesized by free radical polymerization. chemical modification of paam-g-gg by alkaline hydrolysis results in formation of a ph-sensitive co-po...

Journal: :iranian journal of pharmaceutical sciences 0
arshad bashir khan krupanidhi college of pharmacy, bangalore ram sharnagat thakur department of pharmaceutics, krupanidhi college of pharmacy, bangalore, india

the purpose of the research was to formulate microspheres of acyclovir (acv) using mucoadhesive polymers, sodium alginate and chitosan. calcium chloride was used as the ionotropic gelling agent. sodium alginate was crosslinked by calcium chloride leading to a slower release of the drug. chitosan which is a cationic polymer interacted with sodium alginate, an anionic polymer, to form an interpol...

Maryam Payan Mohsen Tafaghodi, Syyed Abolghasem Sajadi Tabasi

     The goal of this study was to prepare and characterize alginate microspheres as an antigen delivery system and adjuvant for immunization against leishmaniasis. Microspheres encapsulated with autoclaved Leishmania major (ALM) and Quillaja saponin (QS) were prepared by an emulsification technique and characterized for size, encapsulation efficiency and release profile of encapsulate...

The objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (MA) using two polymers with different characteristics as ethylcellulose (EC) and/or cellulose acetate phthalate (CAP). Microspheres were prepared by the modified emulsion solvent evaporation (MESE). The effect of drug-polymer interaction was studied for each of microspheres. Important param...

Kamla Pathak, Sonam Singh,

The aim of the present work was to assess the feasibility of Acconon MC8-2 EP/NF as a bioadhesive material for developing controlled release gastroretentive microsponges of loratadine. Modified emulsion-solvent diffusion method was employed for the preparation of microsponges (F1-F9) based on  32 factorial design. The amount of ethyl cellulose (EC) and polyvinyl alcohol (PVA) were selected...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه سیستان و بلوچستان - دانشکده مهندسی شیمی 1391

there is no doubt that human being needs to become integrated with industry and industry needs to be progressed, daily. on the other hand, serious events in industrial units specially in oil industries has been shown that such damages and events are industry related ones. the consequence of such events and damages which resulted in chemical and poisoned explosions and loss of life and property ...

Journal: :iranian journal of basic medical sciences 0
mohsen tafaghodi school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmaceutical research center, mashhad university of medical sciences, mashhad, iran abolghasem sajadi tabassi school of pharmacy, mashhad university of medical sciences, mashhad, iran pharmacological research center of medicinal plants, mashhad university of medical sciences, mashhad, iran nafiseh amiri school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective(s) several antigens, adjuvants and delivery systems have been evaluated for induction of protective immune responses against leishmaniasis, but most of them have been inefficient. in this study, plga nanospheres as antigen delivery system cpg-odn as an immunoadjuvant for increasing the immune responses against autoclaved leishmania major (alm) were prepared and characterized. material...

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