OBJECTIVE To compare the outcome of renal replacement treatment in patients with diabetes mellitus and in non-diabetic patients with end stage renal failure. DESIGN Retrospective comparison of cases and matched controls. SETTING Renal unit, Western Infirmary, Glasgow, providing both dialysis and renal transplantation. PATIENTS 82 Diabetic patients starting renal replacement treatment betw...

A neonate with severe oligo-anuric renal failure during multi-organ failure survived with prolonged renal replacement therapy Sir, Here, we report a neonate with severe oligo-anuric renal failure during multi-organ failure who survived with prolonged renal replacement therapy. A female neonate, born at a gestational age of 39 weeks and 3 days, weighing 2780 gram, presented cyanosis on Day 15. S...

Renal replacement lipomatosis of the kidney is characterized by renal sinus and perirenal fat proliferation. It is associated with chronic infection and calculi, commonly central, often obstructing. The kidney may be large or small but is usually nonfunctioning. Most of the renal parenchyma has been replaced by fat, pararenal fascia are thickened, and there may be fistulae. We reported radiolog...

as the world’s population continues to age, practitioners encounter increasing numbers of older patients with end-stage renal disease (esrd) who require renal replacement therapy (rrt). conservative management may be considered in older patients and has been shown to offer comparable survival rates and hospital-free days to rrt patients. at present, for those who choose rrt, hemodialysis is the...

BACKGROUND Acute kidney injury (AKI) is associated with a substantially increased risk of mortality for many hospitalized patients. It has been suggested that early initiation of renal replacement treatment has a favorable outcome in critically ill patients complicated with AKI. However, results of studies evaluating the effect of early initiation strategy of renal replacement treatment on AKI ...

BACKGROUND AND OBJECTIVES Current recommendations for piperacillin-tazobactam dosing in patients receiving continuous renal replacement therapy originate from studies with relatively few patients and lower continuous renal replacement therapy doses than commonly used today. This study measured the pharmacokinetic and pharmacodynamic characteristics of piperacillin-tazobactam in patients treated...

OBJECTIVE To evaluate the prognostic value of platelet counts in acute kidney injury patients requiring renal replacement therapy. METHODS This prospective cohort study was performed in three tertiary-care hospitals. Platelet counts were obtained upon admission to the intensive care unit and during the first week of renal replacement therapy on days 1, 3, 5 and 7. The outcome of interest was ...

BACKGROUND Acute kidney injury is a common and devastating complication of critical illness, for which renal replacement therapy is frequently needed to manage severe cases. While a recent systematic review suggested that "earlier" initiation of renal replacement therapy improves survival, completed trials are limited due to small size, single-centre status, and use of variable definitions to d...

The management of patients with concomitant xenobiotic toxicity and multisystem trauma can be complex. While hemodialysis is generally the modality of choice for extracorporeal elimination of salicylates, the potential for large volume shifts and hypotension may pose a risk in patients with traumatic brain injury. An alternative therapy to hemodialysis is continuous renal replacement therapy, w...