In 2004, McLaughlin et al. discovered a phenomenon in the radio emission of PSR J0737−3039B (B) that resembles drifting sub-pulses. The repeat rate of the sub-pulses is equal to the spin frequency of PSR J0737−3039A (A); this led to the suggestion that they are caused by incidence upon B’s magnetosphere of electromagnetic radiation from A. Here we describe a geometrical model which predicts the...

Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disease that has been linked to deletions within a tandem array of 3.2 kb repeats adjacent to the telomere of 4q. These repeats are also present in other locations in the human genome, including the short arms of all the acrocentric chromosomes. Here, we examine two models for the role of this repeat in FSHD. F...

Genetic variants within the dopamine D4 receptor gene (DRD4) are among the strongest and most consistently replicated molecular genetic findings in attentional functioning as well as attention deficit hyperactivity disorder (ADHD). Functionally, the 7-repeat allele of the DRD4-48 base pair repeat gene leads to a sub-sensitive postsynaptic D4 receptor, which is expressed at a particularly high d...

Bovine genital campylobacteriosis is one of the most economically important diseases of dairy cattleresulting in lowered fertility, embryo mortality and abortion, repeated returns to service, reduced pregnancyrates and extended calving intervals. While the occurrence of repeat breeding syndrome and abortions arereported from many Iranian dairy cattle farms, little information is available regar...

Well constructed sub-population databases are fundamental to the application of DNA-based forensic statistics. The size of such databases can affect the ability to examine adequately statistical or population genetic features, and the integrity of both the DNA profile and associated ethnicity information is also of importance. Use of short tandem repeat (STR) DNA profiling technology and the th...

Background: The myotonic dystrophies (DM1, DM2) are the most common adult muscle diseases and characterized by multisystem involvement. DM1 has been described in diverse populations, whereas DM2 seems to occur primarily European Caucasians. Both caused expression of expanded microsatellite repeats. In DM1, there is a reservoir premutation alleles; however, have no reported alleles for DM...

background: expansion of gaa trinucleotide repeats is the molecular basis of friedreich’s ataxia (frda). precise detection of the gaa expansion repeat in frataxin gene has always been a challenge. different molecular methods have been suggested for detection of gaa expansion, including; short-pcr, long-pcr, triplet repeat primed-pcr (tp-pcr) and southern blotting. the aim of study was to evalua...

We study data on variation in 52 worldwide populations at 377 autosomal short tandem repeat loci, to infer a demographic history of human populations. Variation at di-, tri-, and tetranucleotide repeat loci is distributed differently, although each class of markers exhibits a decrease of within-population genetic variation in the following order: sub-Saharan Africa, Eurasia, East Asia, Oceania,...

Jump testing to monitor athletic performance and development has become commonplace in the field of strength conditioning. Verbal cues jump tests, such as drop jump, significant effects on metrics movement strategy. The purpose this study was use a force platform analysis investigate landing depth global flexion lower extremity joints at initial impact between maximize height or minimize ground...