The translation of hypothesis-driven research laboratory findings about basic disease mechanisms into clinically useful tests or therapies, particularly in pediatric diseases, is time-consuming, expensive, and not well supported by traditional research grant mechanisms. Accordingly, the development of new drugs and clinical assays has typically been largely the domain of the pharmaceutical indu...

Since 1990s, Information Technology has developed at speed. With the development of IT and Internet, E-Government affair has become the focus of every government. As an important part of E-Government Affair, E-Government Procurement has a great influence on the development of economy. Based on the situation of Government Procurement of China, this paper states the importance of benefit evaluati...

DURING World War II, the US Army Quartermaster Corps established a Climatic Research Laboratory on the second floor of an old building of the Pacific Mills in Lawrence, MA, on the banks of the Merrimac River. The mission of this organization was to test equipment, particularly clothing, for the use of troops in the field, and the Pacific Mills had been chosen because it housed climatically cont...

Years ago I used to worry about the degree to which I had specialized. Vision is limited enough, yet I was not really working on vision, for I hardly made contact with visual sensations, except as signals, nor with the nervous pathways, nor the structures of the eye, except the retina. Actually, my studies involved only the rods and cones of the retina, and in them only the visual pigments. A s...

Conducting field research in the developing world is, under any circumstances, a complex affair, and the study of information and communication technologies (ICTs) in this context adds yet another series of special challenges. Nevertheless, telecenter research offers tremendous opportunity to understand the role of communication and information in development. More importantly, a participatory ...

Where do intimal smooth muscle cells (SMCs) come from? For many years, the idea that intimal SMCs originated from the underlying media went unchallenged.1 Then, reports2,3 began to appear that up to half of the SMCs in the intima of atherosclerotic plaques and injured arteries arose from circulating progenitor cells of bone marrow origin. This new view of intimal SMC formation was potentially i...