Murraya koenigii L. (Rutaceae), commonly known as curry leaf tree, closely associated with south India where the word "curry" originates from the Tamil "kari" for spiced sauces. Curry leaves are a rich source of carbazole alkaloids which possess various biological activities such as antitumor, antioxidant and anti-inflammatory. Curry leaf has a potential role in the treatment of diabetes. Reser...

Comparison of hemodynamic changes (cardiac output, renal plasma flow, and extremity blood flow) observed during reserpine-induced hypotension with those occurring during pentoliniuminduced hypotension suggests better adaptation following reserpine. This difference is believed to be related to the gradation of onset of hypotension. It was found that reserpine-induced hypotension is potentiated b...

IN ANIMALS, reserpine depletes tissues of catecholamines, -3 reduces the response of smooth muscle to tyramine,4' 5 and potentiates the action of norepinephrine.4 6, The decreased response to tyramine probably results from depletion, since the action of this sympathomimetic amine appears to be mediated through the release of norepinephrine.4-6 The cause of hypersensitivity to exogenous norepine...

cium was omitted from the medium, and markedly inhibited by the addition of cocaine. 3. Addition of reserpine or tyramine stimulated the release of catecholamine from the slices. The effect of reserpine was diminished in calcium free medium, but that of tyramine was not affected in calcium free medium. Cocaine had a weak inhibitory effect on the release of catecholamine caused by reserpine but ...

High doses of reserpine induce depletion of biogenic amines. The K-NPPase activity of choroid plexus was determined after one-shot reserpine administration using cerium-based cytochemistry. In normal untreated animals, reaction product was found on the microvilli of the choroidal epithelium but was almost undetectable 3 and 7 days after reserpinization. At 20 days after reserpinization, however...

IN ANIMALS, reserpine depletes tissues of catecholamines, -3 reduces the response of smooth muscle to tyramine,4' 5 and potentiates the action of norepinephrine.4 6, The decreased response to tyramine probably results from depletion, since the action of this sympathomimetic amine appears to be mediated through the release of norepinephrine.4-6 The cause of hypersensitivity to exogenous norepine...

1 Reserpine (1.25 mg/kg i.p.) induced an increase (172% of controls) in the concentration of 1-(4-hydroxy-3-methoxyphenyl)-ethane-1,2-diol sulphate (MOPEG-SO(4)) in rat brain and a decrease in the noradrenaline (NA) concentration to 50% of controls 2 h after injection. At this time the MOPEG-SO(4)/NA ratio was 0.28. Thereafter the MOPEG-SO(4) concentration declined and the NA concentration decr...

IN ANIMALS, reserpine depletes tissues of catecholamines, -3 reduces the response of smooth muscle to tyramine,4' 5 and potentiates the action of norepinephrine.4 6, The decreased response to tyramine probably results from depletion, since the action of this sympathomimetic amine appears to be mediated through the release of norepinephrine.4-6 The cause of hypersensitivity to exogenous norepine...

The antagonistic activity of reserpine pretreatment on ouabain toxicity was investigated in the guinea pig, with attention paid to the water and potassium unbalance caused by diarrhea. Reserpine pretreament alone exhibited no protective action against ouabain toxicity, but it was manifested by the administration of potassium chloride. On the other hand, glucose water was ineffective. There was ...