I performed laboratory bioassays to characterize the acute contact toxicity of oxalic acid (OA) to Varroa destructor (Anderson & Trueman) and their honey bee hosts (Apis mellifera). Specifically, I conducted glass-vial residual bioassays to determine the lethal concentration of OA for Varroa, and I conducted topical applications of OA in acetone to determine the lethal dose for honey bees. The ...

In drug discovery research, residual solvent measurement is an integral part of purity analysis for synthesis of a drug candidate before it is used for toxicity testing. This is usually carried out using gas chromatography (GC) with direct injection sample introduction. This method requires testing compounds to be soluble at high concentrations (>50 mg/mL, usually in DMSO) to achieve acceptable...

Eucalyptus bleached kraft pulp production, an important sector of the Brazilian national economy, is responsible for generating large volume, high pollutant load effluents, containing a considerable fraction of recalcitrant organic matter. The objectives of this study were to quantify the biological activity of the effluent from a eucalyptus bleached kraft pulp mill, characterize the nature of ...

Breast milk concentrations of 4,4'-DDT and its related compounds were studied in samples collected in 2002 and 2006 from two populations of mothers in Manhiça, Mozambique. The 2006 samples were obtained several months after implementation of indoor residual spraying (IRS) with DDT for malaria vector control in dwellings and those from 2002 were taken as reference prior to DDT use. A significant...

Outcome in childhood acute lymphoblastic leukemia is prognosticated from levels of minimal residual disease after remission induction therapy. Higher levels of minimal residual disease are associated with inferior results even with intensification of therapy, thus suggesting that identification and targeting of minimal residual disease cells could be a therapeutic strategy. Here we identify hig...

PURPOSE To identify patterns of enhancement in the internal auditory canal (IAC) on MR studies after removal of an acoustic neuroma, including changes in those patterns with time; to evaluate signal and enhancement of the labyrinth; to differentiate normal postoperative findings from those suggesting residual tumor; and to describe MR hallmarks of surgical approaches. METHODS We reviewed the ...

Toxicity of raw and bio-slurry treated oily sludge (OS) on Nitrobacter species was determined using standard analytical procedures. The total petroleum content the OS 116.44 ± 3.57 g/kg. TPH rich with Saturate (40.46 0.73 %). This followed by Aromatics (27.94 0.50 %) Asphaltenes (26.58 0.90 %), while NSO fraction had least proportion (5.75 0.47 Contamination coastal soil increased residual conc...

The popular use of ciprofloxacin is often irrational, so it causes environmental pollution such as resistance. solution to overcome due degradation by using TiO2 nanoparticles. nanoparticles performance influenced environment light source, pH solvent, duration lighting and mass. residual levels determination was carried out a UV-Vis spectrophotometer. Toxicity test products with used Escherichi...

Residual solvents are organic volatile impurities that can occur in the manufacture of Active Pharmaceutical Ingredients (APIs). analysis pharmaceutical products is necessary not only because they represent a potential risk for human health due to their toxicity and undesirables side effects, but also may affect physicochemical proprieties product. The main objective this work was 29 residual s...

amitraz is one of the pesticides which is used in a vast area for controlling of the common pistachio psyllid, agonoscena pistaciae (hem.: aphalaridae). in this study the synergistic effect of piperonyl butoxide (pbo) on the toxicity of amitraz on adults of rafsanjan population of common pistachio psyllid was evaluated by residual contact vial (rcv) in laboratory conditions. the results showed ...