OBJECTIVE We sought to assess insulin secretion/insulin resistance index in predicting the risk for future type 2 diabetes RESEARCH DESIGN AND METHODS A total of 1,551 nondiabetic subjects from the San Antonio Heart Study received an oral glucose tolerance test (OGTT) with measurement of plasma glucose and insulin concentrations at 0, 30, 60, and 120 min at baseline and after 7-8 years of fol...

Background: Obesity in children is now an increasing health risk worldwide in which the insulin-resistance can be present. Studies have linked a diet rich in n-3 fatty acids with a lower prevalence of insulin-resistance. Objective: To compare the levels of eicosapentaenoic acid among obese children with and without insulin-resistance. Materials and Methods: In 56 randomly school-age children wi...

objective: the aim of the present study is assessment of insulin resistance (ir) in obese women by tyg-index and compared with the homa-ir index. materials and methods: this cross-sectional study was performed on 61 obese women aged 18-45 years. weights, height, waist circumference (wc) were measured and body mass index (bmi) was calculated and recorded. a sample of fasting serum was collected ...

We have studied the effect of i.v. metoclopramide on renal vascular resistance in nine healthy volunteers. Peak systolic and end-diastolic frequencies were measured using duplex Doppler ultrasound of a renal interlobar artery, before and after the administration of i.v. metoclopramide 10 mg, and the resistance index derived. There was no significant change in mean arterial pressure or resistanc...

OBJECTIVE The purpose of this study was to investigate the validity of established insulin resistance indexes, based on fasting blood parameters, in a stable renal transplant population. RESEARCH DESIGN AND METHODS Fasting insulin, homeostasis model assessment (HOMA), the quantitative insulin sensitivity check index (QUICKI), and McAuley's index were assessed for correlation and agreement wit...

BACKGROUND Patients with Fontan circulation have reduced exercise capacity. The absence of a presystemic pump may limit flow through the pulmonary circulation, restricting ventricular filling and cardiac output. We evaluated exercise hemodynamics and the effect of sildenafil on exercise hemodynamics in Fontan patients. METHODS AND RESULTS Ten Fontan patients (6 men, 20±4 years) underwent card...

PURPOSE The aim of this study was to investigate factors that influence arterial Doppler waveforms in an in vitro phantom to provide a more accurate and comprehensive explanation of the Doppler signal. METHODS A flow model was created using a pulsatile artificial heart, rubber or polyethylene tubes, a water tank, and a glass tube. Spectral Doppler tracings were obtained in multiple combinatio...

OBJECTIVE To investigate whether maternal anxiety in the third trimester is associated with an increased uterine artery resistance index. DESIGN Cohort based study. SUBJECTS 100 pregnant women, with a mean gestation of 32 weeks. OUTCOME MEASURES Self rating Spielberger questionnaire for state anxiety and trait anxiety, and uterine blood flow waveform patterns as assessed by colour Doppler...