Increased pulmonary vascular resistance in preterm newborn infants with respiratory distress syndrome is suggested, and endothelin-1 plays an important role in pulmonary vascular reactivity in newborns. We determined umbilical cord blood and neonatal (second sample) levels of endothelin-1 in 18 preterm newborns with respiratory distress syndrome who had no clinical or echocardiographic diagnosi...

Increased pulmonary vascular resistance in preterm newborn infants with respiratory distress syndrome is suggested, and endothelin-1 plays an important role in pulmonary vascular reactivity in newborns. We determined umbilical cord blood and neonatal (second sample) levels of endothelin-1 in 18 preterm newborns with respiratory distress syndrome who had no clinical or echocardiographic diagnosi...

Acute respiratory distress syndrome is characterized by a diffuse inflammatory reaction of lung parenchyma induced by a direct insult to the alveolar epithelium (pulmonary acute respiratory distress syndrome) or an indirect lesion through the vascular endothelium (extrapulmonary acute respiratory distress syndrome). The main therapeutic strategy for acute respiratory distress syndrome is the ve...

background: congenital lobar emphysema, also called infantile lobar emphysema, is a respiratory disease that occurs in infants when air enters the lungs and cannot leave easily. it results from cartilage deficiency and bronchomalacia causing distal air trapping and respiratory distress. in this study, we present a case of endobronchial polyp mimicking congenital lobar emphysema. case presentati...

BACKGROUND The assessment of the work of breathing in the definitions of respiratory failure is vague and variable. OBJECTIVE Identify a parsimonious set of signs to describe the work of breathing in hypoxemic, acutely ill patients. METHODS We examined consecutive medical ICU patients receiving oxygen with a mask, non-invasive ventilation, or T-piece. A physician inspected each patient for ...

Neonatal respiratory distress syndrome [4], previously called hyaline membrane disease, is a respiratory disease affecting premature newborns. Neonatal respiratory distress syndrome [4] involves shallow breathing, pauses between breaths that last a few seconds, or apnea, and a bluish tinge to the infant?s skin. The syndrome occurs when microscopic sacs called alveoli in infant lungs do not prod...