The Mga protein in B514Sm, a Streptococcus pyogenes strain isolated as a mouse pathogen, contains amino acid substitutions at conserved sites that render the protein defective. Replacement of mga50 with the functional homolog mga4.1 restored full expression of Mga-regulated proteins. Restoration of Mga function did not affect fibrinogen binding, nor did it affect virulence in several mouse mode...

Appropriate reconstruction of the bone anatomy is necessary to obtain a good functional outcome after total knee replacement (TKR) (1, 2). Restoration of the native posterior femoral offset has been described as a significant prognostic factor, mainly for completion of a good range of motion in flexion (3). The measurement of the posterior offset prior to the TKR on standard X-ray or CT-scan ma...

INTRODUCTION The restoration of posterior teeth with composite restoration is a common clinical practice nowadays. Opinions regarding posterior composite restorations vary among dentists. The aim of the present study was to determine the knowledge and opinions of general dental practitioners towards composite resins for posterior teeth restorations. MATERIALS AND METHODS A questionnaire was d...

Immediate chairside replacement of an extracted anterior tooth may contribute to a patient's comfort, treatment acceptance, and expectations of treatment; however, fabrication of a custom restoration in the anterior region of the mouth may result in an esthetic compromise for patients during the fabrication period. Chairside tooth replacement is an excellent application of fiber-reinforced comp...

Replacement of dental restorations has been the traditional treatment for defective restorations. This five-year prospective clinical trial evaluated amalgam restorations with localized defects that were treated by means of repair or refurbishing. Fifty-two patients (50% female and 50% male, mean age 28.3 ± 18.1 years, range 18-80) with 160 class I and class II defective restorations were inclu...

We aimed to document the pre-operative expectations in Korean patients undergoing total knee replacement using an established survey form and to determine whether expectations were influenced by sociodemographic factors or pre-operative functional status. Expectations regarding 17 items in the Knee Replacement Expectation Survey form were investigated in 454 patients scheduled for total knee re...

Secondary caries, the lesion at the margin of a restoration, has been widely considered as the most important and common reason for restoration replacement, regardless of the restorative material type [Collins et al., 1998; Dahl and Eriksen, 1978; Deligeorgi et al., 2001; Friedl et al., 1995; Mjör, 2005; Mjör and Toffenetti, 2000;]. As it develops after the initial caries has been removed and r...

OBJECTIVES Our objectives were (1) to report operative and long-term mortality in patients submitted to anterior surgical ventricular restoration, (2) to report changes in clinical and cardiac status induced by surgical ventricular restoration, and (3) to report predictors of death in a large cohort of patients operated on at San Donato Hospital, Milan, Italy. METHODS A total of 1161 consecut...

  Objective: Repair of an indirect restoration is usually preferred over its replacement. This study aimed to evaluate the effect of silane in different surface preparation techniques on the bond strength of direct to indirect composite resin.   Methods: For this in vitro experimental study, 48 indirect composite cubes were fabricated, divided into 4 groups of 12 and subjected to the following ...

One of the most common methods dental treatment in a minimally invasive concept is direct restoration carious damaged teeth or with trauma. In this article represents clinical case old unsatisfactory restorations replacement 36, 37 followed by hard tissue class II defects using composite taking into account aesthetic and biomechanical aspects.