Measurement of isotope accumulation in an organ is often used to assess that organ's removal of blood cells labelled with the isotope. This technique is only valid if the isotope does not elute from the organ. Elution of 111In from the liver and spleen has been investigated in 14 subjects following intravenous injection of heat-damaged erythrocytes labelled with 111In. The elution rate from the...

Reticulum cells in the lymph nodes and the spleen, and histiocytes in the subcutaneous connective tissue were both studied with electron microscope. Reticulum cells showed marked development of endoplasmic reticules both rough and smooth varieties, and were classified with their fine structures into the mature, ingesting, immature and productive types. In the productive in flammatory lesions, t...

Splenectomy can treat conditions characterized by hemolysis or thrombocytopenia caused autoantibodies splenic reticuloendothelial function, as well disorders massive splenomegaly and hypersplenism with cytopenias, such hereditary spherocytosis, transfusion-dependent thalassemia, immune thrombocytopenia, autoimmune hemolytic anemia, marginal zone lymph is no longer used for Hodgkin disease stagi...

spleen is a major component of the reticuloendothelial system and functions as a filtering system for the encapsulated bacteria especially in children. knowing the spectrum of conditions leading to splenectomy in any geographic area is important to decrease the number of unnessesary splenectomies. here we report the causes of splenectomy in three major general referring hospitals in shiraz, the...

It is generally accepted that of the manyways of studying the problems relating to the reticuloendothelial system splenectomy is one of the most valuable and popular methods. The spleen being one of the organs rich in reticuloendothelial cells, the removal of the organ is assumed to result both in the lowering of the total number of reticuloendothelial cells and in the diminution of the functio...

The way in which iron is handled by the duodenal mucosa, the reticuloendothelial system, the hepatic parenchymal cell, and the normoblast was investigated in copper-deficient swine.Copper-deficient swine failed to absorb dietary iron at the normal rate. Increased amounts of stainable iron were observed in fixed sections of duodenum from such animals. When (59)iron was administered orally, the m...

An in vivo assay to quantify simultaneously two important components of hepatic reticuloendothelial system (RES) function--clearance and phagocytic killing--was developed in the rat. Intravenously injected E. coli labeled with Na51Cr and 5-[125I]-iodo-2'-deoxyuridine were cleared rapidly from the blood primarily by the liver. While hepatic 51Cr levels remained stable for 24 h following inoculat...