Acute myeloid leukemia (AML) cells are relatively resistant to tumor necrosis factor alpha-related apoptosis-inducing ligand (TRAIL). We previously reported that triptolide, a potent anticancer agent from a Chinese herb, decreases XIAP in leukemic cells. We evaluated the combination of triptolide and TRAIL and found synergistic promotion of apoptosis in AML cells. XIAP-overexpressing U937 cells...

The human bladder cancer cell line MGH-U1 (also designated 1-24 or EJ) contains an activated c-Ha-ros oncogene, which is amplified as compared to normal human fibroblasts. We have generated sublines from the MGH-U1 cell line: the MCH-U1/OCI subline was generated by dissociating spheroids formed from MGH-U1 cells; the I l-m/l-, and OCI-m/Fi were generated by in vivo passage of experimental lung ...

BACKGROUND Occult hepatitis C virus infection (OCI) is recognized by finding hepatitis C virus (HCV) RNA in hepatocytes without detectable anti-HCV antibodies and viral RNA in plasma. Autoimmune hepatitis (AIH) is a chronic and generally progressive disease without exactly-identified etiology. OBJECTIVES This study aimed to determine the prevalence of OCI among patients with AIH and to evalua...

Mutated nucleophosmin 1 (NPM1) acts as a proto-oncogene and is present in ~30% of patients with acute myeloid leukemia (AML). Here we examined the in vitro and in vivo anti-leukemic activity of the NPM1 and chromosome region maintenance 1 homolog (CRM1) interacting natural product avrainvillamide (AVA) and a fully syntetic AVA analog. The NPM1-mutated cell line OCI-AML3 and normal karyotype pri...

Orthogonal frequency-division multiplexing (OFDM) is one of the most promising techniques for the 4-th generation mobile system. When the OFDM system is applied to cellular environment, it is required to make the transmission scheme robust to other-cell interference (OCI). The use of code division multiplexing (CDM) has been considered to mitigate the OCI in OFDM systems. In cell boundary, it i...

The goals of this work were to: (1) determine the prevalence of clinically significant obsessive-compulsive (OC) symptoms in patients with temporal lobe epilepsy (TLE), (2) characterize the differences in self-reported OC symptoms in patients with TLE and a normative control group, and (3) compare the severity of OC symptoms in right and left hemisphere TLE patients. Patients with TLE (n=30) we...

In this study, the psychometric properties of the Korean version of the OCI-R and the effects of order, gender, and culture on the inventory were examined in a nonclinical and in a clinical sample comprised of 702 college students and 91 patients with OCD. As a result, the original six-factor model is supported by the confirmatory factor analysis. The internal consistency, test-retest reliabili...

This study aims to investigate the role and mechanism of miR-34a in diffuse large B-cell lymphoma (DLBCL). Totally 30 DLBCL patients and 30 reactive lymph node hyperplasia patients were selected as DLBCL group and control group respectively. Lymph node tissues were collected. The miR-34a inhibitors or mimics were transfected into OCI-LY10 cells. RT-qPCR was performed to detect levels of miR-34a...

Other Comprehensive Income (OCI) is the impact of applying fair value accounting, namely difference between assets (liabilities) and their carrying values. Uncertainty about time amount OCI which a medium for tax avoidance. This study provides empirical evidence whether can be used avoidance, data from 504 companies listed on IDX 2016 – 2020. The results show that in Indonesia do not carry out ...