A 47-year-old man presented at our emergency department with sudden-onset dyspnea, chest pain, tachycardia, and bilateral leg swelling. He had hypotension and tachycardia. His oxygen saturation was 82% and plasma D-dimer level was 455 μg/L. An electrocardiogram showed sinus tachycardia and an S1Q 3T3 pattern. Transesophageal echocardiography (TEE) revealed a large thrombus (cross-sectional area...

OBJECTIVES Our purpose was to determine whether atrial fibrillation (AF) patients have alterations in sarcoplasmic reticulum (SR) Ca2+ regulatory proteins in the atrial myocardium. BACKGROUND Clinically, AF is the most frequently encountered arrhythmia. Recent studies indicate that an inability to maintain intracellular Ca2+ homeostasis with a consequent increase in membrane-triggered activit...

The mechanisms of supraventricular tachycardia were investigated in 35 children. Intracardiac electrograms including His bundle potentials were recorded. Atrial pacing and single premature atrial stimuli were performed in the right atrium. Tachycardia was observed and the mechanism elucidated in 33 patients. The atrial activation sequence during tachycardia, including high right atrium, low lat...

The M-mode and two dimensional echocardiographic features are described of a patient with rupture of a sinus of Valsalva aneurysm into the right atrium. A clear echo-free zone arising from the tip of the aneurysm is visualised in the right atrium in diastole by peripheral injection of echocardiographic contrast material. At surgery a fistula was seen between the non-coronary cusp and the right ...

A 42-year-old woman admitted with debilitation and engorgement both lower extremities. Transthoracic two-dimensional echocardiography, abdominal ultrasound and computerized tomography revealed a lobulated pelvic mass, a mass within right internal iliac vein, both common iliac vein, as well as the inferior vena cava, extending into the right atrium. In addition, echocardiography and abdominal ul...

Hyperthyroidism has been associated with atrial fibrillation (AF), however, hyperthyroidism induced ion channel changes which may predispose to AF have not been fully elucidated. To understand the electrophysiological changes occurring in left and right atrium with hyperthyroidism, the patch-clamp technique was utilized to compare action potential duration (APD) and whole cell currents in myocy...

Fig. 1. (a) TOE, modified bicaval view, demonstrates a ‘mass’ in close association to the right atrium (white arrow), (b) TruFISP cardiac magnetic resonance demonstrates that the aneurysm (white arrow) has a perfused central lumen and there was perfusion of the distal right coronary artery, (c) multislice CT demonstrates a grossly aneurysmal saphenous vein graft with a large amount of mural thr...