It has been suggested that the collaborative cross, a large set of recombinant inbred strains derived from eight inbred mouse strains, would be a powerful resource for the dissection of complex phenotypes. Here we use simulation to investigate the power of the collaborative cross to detect and map small genetic effects. We show that for a fixed population of 1000 individuals, 500 RI lines bred ...

We used quantitative trait loci (QTL) mapping to evaluate the age specificity of naturally segregating alleles affecting life span. Estimates of age-specific mortality rates were obtained from observing 51,778 mated males and females from a panel of 144 recombinant inbred lines (RILs). Twenty-five QTL were found, having 80 significant effects on life span and weekly mortality rates. Generation ...

Little is known about natural genetic variation for survival under oxidative stress conditions or whether genetic variation for oxidative stress survival is associated with that for life-history traits. We have investigated survival in a high-oxygen environment at 2 adult densities using a set of recombinant inbred lines (RILs) isolated from a natural population of Drosophila melanogaster. Fema...

Stripe rust or yellow rust (YR), caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most important diseases of wheat (Triticum aestivum L.). Widespread deployment of resistant cultivars is the best means of achieving durable disease control. The red grain, spring wheat cultivar Napo 63 produced by CIMMYT in the 1960s shows a high level of adult-plant resistance to stripe rust in...

With a high potential to generate biomass, maize stover arises as an outstanding feedstock for biofuel production. Maize presents the added advantage of being multiple exploitation crop source food, feed, and energy. In this study, contrasting groups recombinant inbred lines (RILs) from multiparent advanced generation intercross (MAGIC) population that showed variability saccharification effici...

Soybean (Glycine max L. Merr.) seeds are highly sensitive to the environmental conditions experienced in STORAGE. The objectives of this study were identify QTLs for soybean seed storability by evaluating viability and vigor investigating candidate genes these traits detected QTL regions. These will aid developing cultivars with a high capacity storability. 109 90 recombinant inbred lines (RILs...

Dry root rot (DRR) caused by Rhizoctonia bataticola [(Taub.) Butler] is an emerging disease of chickpea (Cicer arietinum L.) and a serious constraint to production in warm arid regions. To identify the genomic regions conferring resistance DRR, total 182 F9 derived Recombinant Inbred Lines (RILs) were developed from cross between susceptible line BG 212 moderately resistant breeding ICCV 08305....

Gummy stem blight (GSB), a major disease caused by Stagonosporopsis cucurbitacearum (syn. Didymella bryoniae ), has significant losses of watermelon in the United States. The lack progress development resistant cultivars is result complex inheritance resistance and breeding strategies that rely on single-plant selection. Because sources are wild relatives, good fruit quality been difficult to m...