PURPOSE To investigate the very long-term prognosis of patients with uveal melanoma and the clinical characteristics influencing it. METHODS Charts, registry data, and histopathologic specimens of 289 consecutive patients with choroidal and ciliary body melanoma treated in the district of the Helsinki University Central Hospital, Finland, between 1962 and 1981 were audited. Definitions for co...

BACKGROUND To examine the all-cause mortality and uveal melanoma specific mortality among newly diagnosed uveal melanoma patients after five years. Furthermore, we assess of the effect of iris colour and having children on 5-year risk of death after diagnosis of uveal melanoma. Therefore, we assess the performance of an individual prediction model of survival from uveal melanoma. METHODS A co...

Adenomas of the non-pigmented epithelium of the ciliary body are rare neoplasms and most of the studies are in the form of case reports. There are only 27 documented cases of acquired neoplasm of the non-pigmented ciliary epithelium (NPCE) reported in the English literature. In most reports, there was a clinical suspicion of melanoma and the diagnosis of NPCE adenoma was made on histopathologic...

A retrospective study of all cases of iris melanoma in Northern Ireland over a 15-year period was undertaken. A total of 18 cases were identified. Of these, nine were histologically proved to be iris melanomas of various types. Within the period of follow-up two patients died from metastatic deposits. In both cases invasion of the anterior face of the ciliary body was present on histological ex...

8. Angiero F, Torti S, Crippa R, Stefani M. Oral metastasis of ciliary body melanoma. A case report. Minerva Stomatol. 2006;55:401--7. 9. Manganaro AM, Hammond HL, Dalton MJ, Williams TP. Oral melanoma: case reports and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;80: 670--6. 0. de Troya-Martin M, Blazquez-Sanchez N, Fernandez-Canedo I, Frieyro-Elicegui M, Fu...

This study attempts to document the occurrence of tumors with respect to clock hour location and distance from the macula and to evaluate tumor location in relation to retinal topography and light dose distribution on the retinal sphere. Analysis of patterns of tumor initiation may provide new evidence to clarify the controversy regarding the possible light-related etiology of choroidal melanom...

This paper described the first animal model of a virally induced uveal melanoma. Tumors developed following the injection of an RNA tumor virus, i.e., Gardner strain feline sarcoma virus, into the anterior chamber of newborn kittens. Histologically, the tumors were found to be iris and ciliary body melanomas, many of which showed invasion. The histology and ultrastructure of those tumors are de...