Cross-talk between apoptosis and survival signaling pathways is crucial for regulating tissue processes and mitigating disease. We report that anoikis-apoptosis triggered by loss of extracellular matrix contacts-activates a CD95/Fas-mediated signaling pathway regulated by receptor-interacting protein (RIP), a kinase that shuttles between CD95/Fas-mediated cell death and integrin/focal adhesion ...

The restricted isometry property (RIP) for design matrices gives guarantees for optimal recovery in sparse linear models. It is of high interest in compressed sensing and statistical learning. This property is particularly important for computationally efficient recovery methods. As a consequence, even though it is in general NP-hard to check that RIP holds, there have been substantial efforts ...

Rip currents form on beaches worldwide and pose a potential safety hazard for beach visitors. Therefore, effectively identifying rip from scenes providing real-time alerts to managers beachgoers is crucial. In this study, the YOLO-Rip model was proposed detect current targets based popular deep learning techniques. First, characteristics of large target size in images, neck region YOLOv5s strea...

TRAIL (TNF-related apoptosis-inducing ligand) is a member of the tumor necrosis factor superfamily that can induce tumor selective death by up-regulating death receptor 4 (DR4) and DR5 expression. The study aimed to explore the role of RIP and c-FLIP genes in TRAIL induced liver cancer cell HepG2 and Hep3B apoptosis and related mechanism. RIP and c-FLIP silenced HepG2 and Hep3B cell model were ...

With use of the yeast two-hybrid system, the proteins RIP and FADD/MORT1 have been shown to interact with the "death domain" of the Fas receptor. Both of these proteins induce apoptosis in mammalian cells. Using receptor fusion constructs, we provide evidence that the self-association of the death domain of RIP by itself is sufficient to elicit apoptosis. However, both the death domain and the ...

In this paper, Swing-up and Stabilization of the Rotary inverted pendulum (RIP) is done through the fuzzy controller.The attraction of this paper is achieving the above stated aim through lesser number of rules. RIP is highly unstable and nonlinear in nature, so stabilization of the RIP is itself a challenging task. Swing-up mechanism in RIP is a type of unstable mechanism which is done effecti...

Purpose: This study was initiated to evaluate incidence, grade and dosimetric correlation of Clinical Radiation Induced Pneumonitis (RIP) (≥ grade 2) in lung cancer patients undergoing radical radiotherapy. Methods and Materials: From August, 2012 to November, 2013, 85 lung cancer patients received curative 3D CRT. On follow up 14 patients developed symptomatic pneumonitis (≥ Grade 2 as per RTO...

Regulated intramembrane proteolysis (RIP) is a critical mechanism for intercellular communication and regulates the function of membrane proteins through sequential proteolysis. RIP typically starts with ectodomain shedding of membrane proteins by extracellular membrane-bound proteases followed by intramembrane proteolysis of the resulting membrane-tethered fragment. However, for the majority o...

INTRODUCTION The clinical feasibility of noninvasive imaging of interstitial alterations after myocardial infarction (MI) was assessed using a technetium-99m-labeled RGD imaging peptide (RIP). In experimental studies, RIP has been shown to target integrins associated with collagen-producing myofibroblasts (MFB). METHODS AND RESULTS Ten patients underwent myocardial perfusion imaging (MPI) wit...

We propose kernel block restricted isometry property (KB-RIP) as a generalization of the well-studied RIP and prove a variety of results. First, we present a “sumof-norms”-minimization based formulation of the sparse recovery problem and prove that under suitable conditions on KB-RIP, it recovers the optimal sparse solution exactly. The Group Lasso formulation, widely used as a good heuristic, ...