abstract background and purpose: distress is an important issue with significant effects on nurses and patients in the nursing profession. this study aimed to investigate the effects of mindfulness-based cognitive therapy (mbct) on the distress tolerance of nurses with job burnout. methods: this quasi-experimental study was conducted with a pretest-posttest design and a control group. study pop...

objectives : this study aimed to investigate the long-term effects of mindfulness-based therapy on improving life quality of patients with irritable bowel syndrome. method : this was an experimental study including 24 patients (12 from each group) with ibs syndrome were selected based on the romeiii criteria and were randomly placed in the test and control groups. in both groups, the scales of ...

objectives: this study aimed at investigating the effectiveness of mindfulness based cognitive therapy (mbct) in management of pain and functional limits of chronic pain patients. methods & materials: in this semi-experimental study, 30 volunteer female patients suffering from chronic pain attending a clinical assessment for treatment of chronic pain were recruited using the convenience samplin...

The discovery that RNA can act as a biological catalyst, as well as a genetic molecule, indicated that there was a time when biological reactions were catalysed in the absence of protein-based enzymes. It also provided the platform to develop those catalytic RNA molecules, called ribozymes, as trans -acting tools for RNA manipulation. Viral diseases or diseases due to genetic lesions could be t...

OBJECTIVE We report data on 11 patients with neurological symptoms and human immunodeficiency virus (HIV) cerebrospinal fluid (CSF) viremia contrasting with suppressed plasma HIV RNA during receipt of combined antiretroviral therapy. DESIGN We retrospectively identified instances of central nervous system (CNS) symptoms in patients who had been receiving stable combination antiretroviral ther...

daily. Patients receiving alisporivir as IFN-free treatment who achieved undetectable HCV–RNA levels (below 25 IU/mL) at week 4 continued with initial treatment. Patients with detectable HCV–RNA levels were given add-on IFN and continued with ALV plus PR triple therapy from week 6 to week 24. Dr. Pawlotsky reported a greater than 3 log reduction in mean HCV–RNA levels over the first 4 weeks wit...

Although results of IFN alpha therapy in chronic hepatitis C (C-CH) patients co-infected with TT virus (TTV) have been reported, no results of IFN beta therapy or IFN beta and alpha combination therapy have been reported. In this study, we retrospectively investigated whether co-infection with TTV affects the results of IFN therapy by using stored sera from 60 C-CH patients co-infected with TTV...