Introduction: Various efforts have been made to reduce post tonsillectomy pain in children. The present study was undertaken to evaluate the efficacy and safety of Ropivacaine in post-operative pain management in these children. Materials and Methods: This study is a Randomized control study on 140 patients between 4 - 12 years of age, in whom tonsillectomy was performed in a ...

Abstract Purpose In this paper, we describe six cases, where patients were falsely treated with pre-filled ropivacaine solution instead of medical saline for postoperative settings. Two the died because fatal concentrations in blood, four survived no further physical injury, and two them showed typical intoxication symptoms. The collected blood urine samples deceased, as well surviving patients...

Purpose: We report a case in which lipid therapy successfully treated both immediate central nervous system toxicity and delayed cardiovascular collapse after ropivacaine administration. Case Details: A 54 year old female with a history of hypertension, anxiety and sleep apnea was given bilateral paravertebral blocks with a total of 45 mL 0.5% ropivacaine. Approximately 15 minutes after the blo...

Ropivacaine, a new local anesthetic, is currently being investigated for the treatment of ulcerative colitis, with promising results so far. The aim of this study was to examine anti-inflammatory properties of ropivacaine with regard to its effects on vascular permeability and inflammatory leukocyte behavior in vivo. The effects on leukocyte rolling, firm adhesion and vascular permeability were...

BACKGROUND AND OBJECTIVES In addition to local anesthetic action, ropivacaine has clinically significant vasoconstrictor effects, which may be observed at infiltrative anesthesia, making it an important anesthetic for field blockade. This study aimed at characterizing the constrictor mechanism of ropivacaine on smooth muscles. METHODS Norepinephrine concentration-effect curves in the absence ...

We investigated the safety of LIA (local infiltration analgesia) combined with retransfusion of drained blood. Total knee arthroplasty patients received two peri-articular injections during surgery followed by continuous infusion, both with ropivacaine (567 mg). Ropivacaine plasma concentrations were determined in blood samples taken at 0, 3, 6 and 24 hours postoperatively. The collected shed b...

We reviewed the Chinese and English literature for efficacy and tolerability data as well as pharmacological properties of ropivacaine in Chinese patients. Ropivacaine is a long-acting amide local anesthetic agent that elicits nerve block via reversible inhibition of sodium ion influx in nerve fibers. The available evidence in the literature on anesthesia practice indicates that ropivacaine pro...

BACKGROUND The current study was designed to test the hypothesis that the increased duration of analgesia caused by adding dexmedetomidine to local anesthetic results from blockade of the hyperpolarization-activated cation (I(h)) current. METHODS In this randomized, blinded, controlled study, the analgesic effects of peripheral nerve blocks using 0.5% ropivacaine alone or 0.5% ropivacaine plu...

While writing the article, we analyzed all studies related to ropivacaine for first half of 2021, which were published in PubMed. Previous review articles on also analyzed.
 Purpose: collection and analysis latest research results ropivacaine. Assessment place modern regional anesthesia.

Background. Intraperitoneal nebulization of ropivacaine reduces postoperative pain and morphine consumption after laparoscopic surgery. The aim of this multicenter double-blind randomized controlled trial was to assess the efficacy of different doses and dose-related absorption of ropivacaine when nebulized in the peritoneal cavity during laparoscopic cholecystectomy. Methods. Patients were ran...