BACKGROUND There are a few studies about commissioning mothers' understanding from the surrogacy during 9 months of waiting for delivery in Iran and other countries. This study was conducted with an aim to explore and explain the nature of concerns (experiences) of commissioning mothers. MATERIALS AND METHODS A qualitative design with a conventional content analysis approach was used to gathe...

Background Polycystic ovary syndrome (PCOS) is a frequent condition in reproductive age women with a prevalence rate of 5-10%. This study intends to determine the relationship between PCOS and the outcome of assisted reproductive treatment (ART) in Tehran, Iran. MATERIALS AND METHODS In this historical cohort study, we included 996 infertile women who referred to Royan Institute (Tehran, Iran...

Royan B(1) stem cell can be differentiated to specialized cell types including cardiomyocytes. This developmental change is accompanied with expression of various K(+) channel types. The aim of this study was to detect functional expression of K(+) currents from stem cell stage and one week and two weeks after differentiation into cardiomyocyte. Mouse stem cell derived cardiomyocytes (ES-cardio...

OBJECTIVE This study aimed to evaluate the levels of two oxidative stress (OS) markers including lipid peroxide (LPO) and total antioxidant capacity (TAC) in both serum and follicular fluid (FF) of women with endometriosis after puncture. MATERIALS AND METHODS In this cross-sectional study, a total number of sixty-three women younger than 40 years old with laparoscopy (gold standard for endom...

BACKGROUND Umbilical cord blood (UCB) stem cells allow the transplantation of partially human leukocyte antigen (HLA)-matched grafts and are a valuable resource for the treatment of hematologic malignancies and heritable hematologic, immunologic and metabolic diseases, especially when a compatible bone marrow donor is unavailable. The aim of this study was to determine how many ethnic groups in...

Abstract Background The aim of this study is to compare anxiety, depression, body image, self-esteem, sexual function, and quality life (QoL) between infertile women control fertile undergoing tubal ligation (TL) using condom. Methods This cross-sectional was conducted on 600 in three groups with or without TL (200 each group), who met the inclusion criteria. They were selected from Royan Insti...

BACKGROUND Septins are an evolutionary conserved group of GTP-binding and filament-forming proteins that have diverse cellular roles. An increasing body of data implicates the septin family in the pathogenesis of diverse states including cancers, neurodegeneration, and male infertility. OBJECTIVE The objective of the study was to evaluate the expression pattern of Septin14 in testis tissue of...

BACKGROUND Several studies have assessed the correlation of fetal choroid plexus cyst (CPC) and the risk of congenital anomalies, but few ones have discussed isolated CPC (with no other abnormal sonographic finding). OBJECTIVE The aim of this study was to determine the outcome of isolated fetal choroid plexus cyst and to specify its clinical significance. MATERIALS AND METHODS This cross se...

Royan Institute International Journal of Fertility and Sterility Vol 10, No 2, Jul-Sep 2016, Pages: 264-266 In in vitro fertilization (IVF) programme, the advantages of mild-stimulation have long been appreciated, while there was a called for more patient-friendly approach in ovarian stimulation around 20 years ago (1). However, the concept is yet to get wide-spread acceptance in the IVF commun...

OBJECTIVE The aim of this study is assessment of effects of different assisted reproductive techniques (ART) like in vitro fertilization (IVF) and intra cytoplasmic sperm injection (ICSI) on prelinguistic behavior of infants conceived by these techniques. METHODS In this descriptive, cross sectional study, prelinguistic behavior of 151 full term ART infants of Royan Institute have been assess...